Acetylcholinesterase inhibitors Flashcards

(4 cards)

1
Q

Drugs

A

Donepezil (Aricept)
Galantamine (Razadyne)
Rivastigmine (Exelon)
Neostigmine
Pyridostigmine
Physostigmine

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2
Q

MOA

A

inhibit acetylcholinesterase from destroying ACh, increasing ACh levels

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3
Q

AE/SE

A

GI, bradycardia
Cholinergic crisis (SLUDGE and Killer Bs)

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4
Q

Indication

A

Alzheimer’s
Neo/pyrido are also used for MG
Physostigmine also treats anticholinergic toxicity, MG, neuromuscular blocker reversal

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