Topiramate (Topomax) Flashcards
(3 cards)
1
Q
MOA
A
Prolong Na+ channel inactivation, blocks specific calcium channels, blocks glutamate GABA agonist
2
Q
Indications
A
Seizure disorders
Migraines
Off label for bipolar and eating disorder, essential tremors
3
Q
AE/SE
A
CNS effects
weight loss
reduced sweating
teratogenic
increased suicide risk
May decrease oral contraceptive effectiveness
