Skeletal muscle relaxants Flashcards
(5 cards)
1
Q
Drugs
A
Baclofen
Carisoprodol (Soma)
Methocarbamol (Robaxin)
Cyclobenzaprine (Flexeril)
Dantrolene
2
Q
MOA
A
Generally act as CNS depressant (do not act directly on skeletal muscle)
Dantrolene suppresses release of calcium, inhibiting muscle contraction
3
Q
Indication
A
Spasticity due to spinal cord injury, MS, cerebral palsy
Dantrolene: Malignant hyperthermia
4
Q
AE/SE
A
CNS depression, N/V
Cyclobenzaprine can also have anticholinergic effects
Dantrolene: Weakness (Black box warning - hepatotoxicity
5
Q
Patient ed
A
Do not take with other CNS depressants or alcohol
Take with food
