Botulinum toxin

Question 1

Drug

Answer 1

Onabotulinumtoxin A

Question 2

MOA

Answer 2

Muscle inactivation - onset days to weeks, duration is several months

Question 3

Indications

Answer 3

Chronic migraines
Overactive bladder
Cervical dystonia (neck spasms)
Hyperhidrosis (excessive sweating)
Spasticity
Strabismus (eye misalignment)
Aesthetics (wrinkles, facial lines)

Question 4

AE/SE

Answer 4

Common effects include local pain at injection site, headache, flu-like symptoms, muscle weakness

Question 5

Patient ed

Answer 5

Adverse effects can occur within hours/days/weeks
Avoid rubbing the area to prevent toxin from spreading to unintended muscles