Valproate Flashcards

(4 cards)

1
Q

Drug

A

Valproic acid (Depakote)

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2
Q

MOA

A

Prolong sodium channel inactivation
GABA agonist

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3
Q

Indication

A

Seizure disorder
Migraines
Bipolar disorder

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4
Q

AE/SE

A

Weight gain
Thrombocytopenia
SJS
Black box: hepatotoxicity
Highly teratogenic
Pancreatitis
Not used under age 2

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