Valproate Flashcards
(4 cards)
1
Q
Drug
A
Valproic acid (Depakote)
2
Q
MOA
A
Prolong sodium channel inactivation
GABA agonist
3
Q
Indication
A
Seizure disorder
Migraines
Bipolar disorder
4
Q
AE/SE
A
Weight gain
Thrombocytopenia
SJS
Black box: hepatotoxicity
Highly teratogenic
Pancreatitis
Not used under age 2