Adaptive/specific Immunity Part 2

Question 1

What is cell mediated immune system? Cells?

Answer 1

T lymphocytes

Question 2

Where does T cells originate?

Answer 2

Bone marrow

Question 3

Where does T lymphocytes mature?

Answer 3

Thymus

Question 4

What does T lymphocytes mainly combat?

Answer 4

Intracellular pathogens

Question 5

Once the T cells leaves the thymus, where does it migrate to?

Answer 5

Secondary lymphoid tissues

Question 6

Once it’s at the secondary lymphoid tissue, it encounters what?

Answer 6

Antigens

Question 7

What is the function of cell mediated immune system?

Answer 7

Intracellular pathogens
Cancer cells

Question 8

T cells with antigen specific TCR encounters antigens, it helps stimulate what? And activates?

Answer 8

Proliferation

Antigen specific T cells

Question 9

T cells recognize antigen when it is already processed and presented to them by?

Answer 9

Antigen presenting cells ( APC )

Question 10

What are the 2 main classes of T cells?

Answer 10

Helper T cells
Cytotoxic T cells

Question 11

What’s another name for Helper T cells?

Answer 11

CD4+

Question 12

Cytotoxic T cells are also called ?

Answer 12

CD8+

Question 13

What’s the function of helper T cells ( CD4+ )

Answer 13

The commander in chief !

Help B cells and other T cells to react

Question 14

What is the function of cytotoxic T cells ( CD8+ )?

Answer 14

Killer cells

Question 15

Who’s the boss? Helper T cells ( CD4+ ) or cytotoxic T cells ( CD8+ )?

Answer 15

Helper T cells

Question 16

Who’s the killer ? Helper T cells ( CD4+ ) or cytotoxic T cells ( CD8+ )?

Answer 16

Cytotoxic T cells ( CD8+ )

Question 17

If someone kills CD4+, what is going to happen with CD8+?

Answer 17

You start dying, cause you don’t have the “ commander in chief “

Question 18

What’s the most famous virus that kills helper T cells? And starts?

Answer 18

HIV
Starts AIDS

Question 19

Activation of a T cell requires Antigen/MHC complex +, a second signal that can only be given by a ?

Answer 19

Professional APC

Question 20

What are professional APC ( antigen presenting cell )? Examples (3)

Answer 20

Dendritic cells
B cells
Macrophages

Question 21

B cells and macrophages must be what and by what in order to be professional APCS?

Answer 21

Must be Activated
By antigens

Question 22

What does MHC mean?

Answer 22

Major histocompatability complex

Question 23

T cells must recognize antigens that contain and cell surface protein called marker ?

Answer 23

Yes
Major histocompatibility complex

Question 24

Are MHC molecules unique to each person?

Answer 24

Yes

Question 25

Does the MHC molecules tell the body what are their cells and what isn’t?

Answer 25

Yes

Question 26

T cells can ONLY see antigen when displayed with MHC molecules?

Answer 26

YES ONLY!

Question 27

How does helper T cells help out Activation of B cells?

Answer 27

MHC class 2 Activate T cells proliferation & secretes cytokines Helper T cell activate Bcells

Question 28

CTLS is?

Answer 28

Cytotoxic T lymphocytes

Question 29

CD8+ recognize antigen presented in associated with what class?

Answer 29

MHC class 1

Question 30

What does CD8+ produce?

Answer 30

Perforin

Question 31

What does perforin do?

Answer 31

A chemical that Lyses cells

Question 32

What is primary immune response?(4) ( encounter with what? What’s first, and follows and finally makes ?)

Answer 32

First encounter with specific antigen IGM is first to be produced IGG next Memory cells are made

Question 33

What is secondary immune response? And is responsible for

Answer 33

Repeat encounter with the same antigen ( naturally or artificially ) is responsible for memory

Question 34

What does the secondary immune response promote? (3)

Answer 34

- stimulation of memory cells - increased levels of IGG - response stronger, faster and more specific

Question 35

Intensity of the antibody mediated immune response can be measured by the?

Answer 35

Antibody titer

Question 36

What is antibody titer?

Answer 36

Amount of antibody in serum