Adrenaline

Question 1

** Adrenaline **
Drug Class

Answer 1

**Sympathomimetic **- Acts on the adrenergic receptors of the sympathetic nervous system
Alpha 1 - Peripheral Vaso Constriction
Beta 1 - Increased force of contraction, Increased heart rate, increased ventricular irritability
Beta 2 - Bronchodilation

Question 2

** Adrenaline**
Indications

Answer 2

• Anaphylaxis
• Life-threatening asthma
• Cardiac Arrest
• Post-ROSC
• Severe croup

Question 3

**Adrenaline **
Preparation for Paediatric
Cardiac arrest and Rosc

Answer 3

Dilute 1 mg in 1 mL (1:1000) adrenaline with 9 mL sodium chloride 0.9% to produce 1 mg in 10 mL (1:10,000 )[100mcg/ml]

Question 4

Adrenaline
Contraindications

Answer 4

Nil

Question 5

** Adrenaline **
Cardiac Arrest
Dose

Answer 5

**Adult **- 1 mg IV/IO, repeat at 3-5 minutes( every 2nd round) as clinically indicated.

Paediatric / Newborn - 10 mcg/kg(0.1ml/kg) of 1:10,000 IV/IO, repeat every 3 - 5 mins (every 2nd round) as cliniically required (max bolus 1mg)

Question 6

Adrenaline
Post ROSC
Dose

Answer 6

Adult - SBP < 100mmHg
(Post 2 x 250mml Sodium Chloride Boluses)

50 microg (0.5 mL) every 3-5 minutes as required to maintain SBP

**Paediatric **- SBP < 80mmHg

1 microg/kg every 3-5 min (max bolus dose 50 microg [0.5ml]) to maintain SBP

Question 7

**Adrenaline **
Anaphylaxis
Life threatening Asthma

Answer 7

Adult - 500mcg (1:1000) IM into lateral mid-thigh
Repeat every 5 minutes no max dose
Paediatric -10 microg/kg (1:1000) IM into lateral mid-thigh ( max bolus dose 500mcg), repeat every 5 minutes no max dose