Droperidol

Question 1

** Droperidol**
Drug Class and Presentation

Answer 1

Antipsychotic
10mg in 2ml (5mg/ml)

IV/IO Dilute 10mg in 2ml with 8ml of NaCl to produce 1mg in 1ml

Question 2

** Droperidol**
Indication

Answer 2

• Disturbed and Abnormal Behaviour (RASS 1 ~ 3) where risk to safety is evident and de escalation has not been effective.

Question 3

** Droperidol**
Contraindications

Answer 3

• Known allergy
• Known Parkinson’s Disease
• Post Ketamine
• Age < 6 years old
• Post-ictal Disturbed & Abnormal Behaviour

Question 4

** Droperidol**
IM (preferred route)
Dose

Answer 4

Adult < 70 yrs
* 5mg (moderate to severe alcohol intoxication)
* 10 mg (nil to mild alcohol intoxication)

Repeat as necessary every 15 mins total max dose 20mg/24 hrs ( all routes)

Switch to IV midazolam only if necessary once total max dose is reached.

Adult > 70 yrs or frail, dementia patients

• 2.5mg (moderate to severe alcohol intoxication)
• 5mg (nil to mild alcohol intoxication)

Repeat as necessary every 15 mins total max dose 10mg/24 hrs ( all routes)

Switch to IV midazolam only if necessary once total max dose is reached.

Question 5

** Droperidol**
IV
Dose

Answer 5

Adult < 70 yrs
* 2.5mg - 5mg titrated to effect

Repeat as necessary every 15 mins to a Total max dose 20mg/24 hrs ( all routes)

Switch to IV midazolam only if necessary once total max dose is reached.

Adult > 70 yrs or frail, dementia patients

• 2.5mg

Repeat as necessary every 15 mins to a total max dose 10mg/24 hrs ( all routes)

Switch to IV midazolam only if necessary once total max dose is reached.