Midazolam

Question 1

** Midazolam **
Drug Class and Presenation

Answer 1

Benzodiazepine– Short acting CNS depressant.

15mg in a 3ml ampoule
IV/IO dilute 15m/3ml with 12m l NaCl in a 20ml syringe (1mg/ml)

Question 2

** Midazolam**
Indications

Answer 2

• Prolonged seizure activity - generalised seizure (≥ 5 minutes) or recurrent seizures
• Focal seizure activity (≥ 5 minutes) with GCS ≤ 12
• Second-line IV agent for sedation maintenance after Droperidol

Question 3

** Midazolam**
Contraindications

Answer 3

Hypersensitivity to Midazolam

Question 4

Midazolam
Dose

Answer 4

Adult < 70 years:
IM
Initial dose:
5 mg
Repeat 5 mg once after 10 min if needed and no IV access.

IV/IO
Initial dose:
2.5 - 5 mg
Repeat 2.5 mg every 5 min as needed (total max dose 15mg)

Adult ≥ 70 years or frail:
IM
Initial dose:
2.5 mg
Repeat 2.5 mg once after 10 min if required and no IV access.

IV/IO
Initial dose:
2.5 mg
Repeat 1 mg every 5 min as needed (Total max 15mg)