Tranexamic Acid

Question 1

Tranexamic Acid. drug Class and presenation?

Answer 1

Antifibrinolytic
1g in a 10ml vial (100mg/ml)

Question 2

List the indications for the use of Tranexamic Acid

Answer 2

• Significant trauma (< 3 hours) with signs of hypovolaemia
• Significant active haemorrhage that requires the use of tourniquet/s or haemostatic/pressure dressing/s
• Suspected head injury (< 3 hours) with GCS motor score of 4 or below
• Severe Primary or Secondary Post-Partum Haemorrhage (> 1000 mL) or PPH with signs of hypovolaemia (birth/bleed occurred < 3 hours)
• Significant post tonsilectomy haemorrhage

Question 3

What is a contraindication for Tranexamic Acid?

Answer 3

• Known hypersensitivity to Tranexamic Acid
• Injury time more than 3hrs

Question 4

What is the adult IV/IO dosage for Tranexamic Acid?

Answer 4

• 1 g slowly over 10 minutes (rapid administration may cause hypotension)

SINGLE DOSE ONLY