Ondansetron

Question 1

**Ondansetron **
Drug Class and presenation

Answer 1

Anti emetic
*4mg wafer
*4mg in 2ml ampoule
IV/IO dilute 4mg(2ml) in 8ml NaCl 0.9% to produce 4mg in 10 ml (0.4mg/ml)

Question 2

**Ondansetron **
Indications

Answer 2

• Moderate to severe nausea
• Active vomiting
• Nausea and vomiting prophylaxis for eye and spinal injuries

Question 3

Ondansetron
Contraindications

Answer 3

• Hypersensitivity to ondansetron
• Treatment with apomorphine (risk of svere hypotension and loss of consciousness)
• Paediatrics less than 2 years old

Question 4

Ondansetron
Oral
Dose

Answer 4

Adult:

• 4 mg oral wafer.
• may be repeated after 15 minutes.
• Total max dose 8mg in 8-hour period.

Question 5

Ondansetron
Intra Muscular (IM)
Dose

Answer 5

Adult:

• 4 mg IM injection
• may be repeated after 15 minutes.
• Total max dose 8mg in 8-hour period.

Question 6

Ondansetron
IV / IO
Dose

Answer 6

Adult:

• 4 mg over at least 30 secs but preferably 3-5 mins
• may be repeated after 15 minutes
• Total max dose 8mg in 8-hour period.

Note: Over 75 years: inject slowly as more susceptible to side effects