Adrenergic (exam 2) Flashcards Preview

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Flashcards in Adrenergic (exam 2) Deck (20)
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1

Alpha 1 receptors have what actions

  • vasoconstriction of blood vessels going to skin, GI tract and kidneys
  • contration of arrector pili, uterus, ureters, internal urethral sphincters 

2

Alpha 2 receptors have what actions?

  • inhibit insulin secretion from pancreas 
  • contraction of GI sphincters

3

Beta 1 receptors have what actions 

  • stimulating increased HR and contractility
  • stimulating renin secretion from kidneys

4

Beta 2 receptors have what actions?

  • vasodilation of blood vessels going to heart, liver, and skeletal muscles
  • bronchodilation of lungs
  • relaxation of uteris, GI tract, and urinary bladder 

5

What effect will adrenergic agonist have on the heart

B1: increase heart rate/ contractility

6

What effect will adrenergic agonist have on the blood vessels

A1: vasoconstriction

B2: vasodilation

7

What effect will adrenergic agonist have on the blood pressure

A1, B1: increase BP

B2: decrease BP

8

What effect will adrenergic agonist have on the lungs

B2: bronchodilation

9

What effect will adrenergic agonist have on the eye

A1: mydriasis

B: increase humor production increase pressure

10

What effect will adrenergic agonist have on the GU tract

  • A1: close sphincter (promote continence)
  • B2: detrusor muscle relaxtion; uterine relaxation (premature labor)

11

What effect will adrenergic agonist have on the CNS

a1: Increase vigilance and focus

12

What effect will adrenergic agonist have on the neuromuscular junction

B2: muscle tremors

13

What are some adrenergic agonist meds?

  • Epinephrine (A1, A2, B1, B2)
  • NE (A1, A2, B1)
  • Isoproterenol (B1, B2)
  • Albuterol (B2)
  • Phenylephrine (A1)
  • Pseudoephedrine (i)
  • Dobutamine (B1)
  • Dopamine (D1, i)

14

What effect will adrenergic antagonists have on the heart

B1: decrease HR and contractility

15

What effect will adrenergic antagonists have on the blood vessels

  • A1: vasodilation
  • B2: decrease vasodilation = decrease perfusion

16

What effect will adrenergic antagonists have on blood pressure

A1, B1: decrease BP

17

What effect will adrenergic antagonists have on the lungs

B2: bronchospasm

18

What effect will adrenergic antagonists have on the eye

B1, B2: decrease aqueous humor production, decrease pressure

19

What are the adrenergic antagonists?

  • Doxazosin, Terazosin, Prazosin (A1)
  • Metoprolol, Atenolol (B1)
  • Propranalol (B1, B2)
  • Labetalol, Carvedilol (A1, B1, B2)
  • Clonidine (A2 agonist)

20

What type of CNS conditions are adrenergic antagonists used for?

Stage fright and essential tremor (B receptors)