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Flashcards in Allergy Deck (21)
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1

Disadvantage of serum specific IgE

High rate of false positives if elevated total IgE (non-specific binding)

2

What type of test is the serum specific IgE

ELISA

3

How many kids will outgrow a milk or egg allergy

80-90%

4

Percent of kids that will outgrow peanut allergy

20%

5

what infants are at high risk of developing food allergy?

those with a first degree relative with an allergic condition

6

what conditions (4) can be managed with immunotherapy

venom allergy, allergic rhinitis, allergic asthma, atopic dermatitis

7

penicillin anaphylaxis is mediated by....

IgE against a major determinant (only 10% a reaction to minor determinant)

8

percent of body surface area involved in toxic epidermal necrolysis

>30%

9

percent of body surface area involved in steven johnsons syndrome

<10%

10

do you give the inactivated influenza vaccine in a kid with egg allergy?

YES, as single dose

11

definition of urticaria

elevated pruritic lesion lasting < 24 hrs

12

if a hive stays in same position > 48 hrs, what should you think of?

urticarial vasculitis, autoimmune condition

13

definition of chronic urticaria

lasts > 6 weeks

14

how do you manage urticaria

standard dose of 2nd generation non-sedating antihistamine

15

what do you do if urticaria doesn't respond to standard dose of second generation non-sedating antihistamine, and symptoms persist x 2 weeks?

increase dose of antihistamine x 4

16

how is hereditary angioedema inherited?

autosomal dominant

17

what causes hereditary angioedema

hereditary C1 esterase inhibitor deficiency

18

how do you treat hereditary angioedema

replacement of C1 inhibitor (blood product)

19

What is the C4 level in hereditary angioedema

decreased in type 1/2

20

what is pollen food allergy syndrome

IgE mediated reaction caused by allergens in plants, to foods that are cross-reactive (ie. birch and peach/apple)

21

can you have a systemic allergic reaction in pollen food allergy syndrome?

yes, up to 10% of patients will have this