Anabolic Reactions Flashcards
(20 cards)
What is OAA?
precursor of several amino acids
What can OAA be converted to?
phosphoenolpyruvate, a precursor of glucose
What is Succinyl-CoA’s purpose?
required for synthesis of cytochromes, chlorophyll, and other tetrapyrrole compounds
What is Acetyl-CoA’s purpose?
necessary for fatty acid biosynthesis
What is the Glyoxylate Cycle and what is the key intermediate?
variation of citric acid cycle, uses glyoxylate as the intermediate
What are the molecules involved in the citric acid cycle?
OAA, Succinyl-CoA, Acetyl-CoA
What are the molecules involved in the glyoxylate cycle?
OAA, Succinate, Acetyl-CoA
What is gluconeogenesis?
synthesis of glucose from phosphoenolpyruvate
How are pentoses for nucleic acids formed?
through decarboxylating glucose
What is ADPG used for?
precursor for glycogen biosynthesis
What is UDPG used for?
precursor of some glucose derivatives needed for biosynthesis of important polysaccharides (ex: n-acetylglucosamine)
What are the 4 different interactions with ammonia?
Dehydrogenase- removes or adds ammonia
Synthetase- adds ammonia
Transaminase- transfers ammonia
Synthase- transfers ammonia
What are fatty acids made out of and what does it require?
made 2 carbons atoms at a time, requires ACP and NADPH
What are the different ways to make pentose sugar?
phosphogluconate pathway, pentose phosphate pathway, and hexose monophosphate shunt
What are the ways to produce pyrimidine?
need a orotic acid with an activated ribose, and there is a UMP intermediate. Products are CTP and TMP
What are the ways to produce purine?
start from amino acids and CO2, add formyl groups with the help of formic acid, and there is a inosinic acid intermediate. Products are AMP and GMP
What does methotrexate, aminopterin inhibit?
tertahydrofolate to TMP
What does 6-mercaptopurine inhibit?
conversion of IMP to AMP
What does 5 fluoropyrimidine inhibit?
conversion of UMP to TMP
What does Sulfonamides inhibit?
block folic acid synthesis
