Anaphylaxis (Adult) Flashcards
(23 cards)
Recite Anaphylaxis CPG Adult
Part 1
Recite Anaphylaxis CPG Adult
Part 2
What is the clinical trigger for this CPG?
Suspected anaphylaxis.
What must be done immediately when anaphylaxis is suspected?
Stop the trigger (e.g. cease infusion, remove food, wash exposed skin).
What is the rule for transport after adrenaline is given?
All patients who receive adrenaline must be transported to hospital.
Why is continuous monitoring important?
Because deterioration can occur suddenly.
What is the typical time of symptom onset?
Usually < 30 mins, can be up to 4 hours.
What does the acronym R.A.S.H. stand for?
Respiratory distress, Abdominal symptoms, Skin/mucosal symptoms, Hypotension.
How is anaphylaxis diagnosed?
• Sudden onset + 2 or more R.A.S.H. symptoms ± antigen exposure, OR
• Isolated hypotension (SBP < 90) after antigen exposure, OR
• Isolated respiratory distress after antigen exposure.
What physical position should be avoided in anaphylaxis?
Do not sit or walk the patient if possible.
What is the first-line medication and dose?
Adrenaline 500 mcg IM (1:1,000).
How often can adrenaline be repeated?
Every 5 minutes as required.
When should MICA be requested?
If risk factors present or poor response to initial adrenaline.
What supportive therapies should be initiated?
• Insert IV
• Provide O₂ as per CPG A0001.
What should be considered if there is inadequate response after 2 IM doses?
Adrenaline infusion as per CPG A0705 Shock.
What therapy is used for stridor or airway oedema?
Adrenaline 5 mg nebulised, consult for repeat.
What are the bronchodilator options?
• Salbutamol 5 mg NEB or pMDI 4–12 doses (20 min intervals)
• Ipratropium 500 mcg NEB or pMDI 8 doses
• Dexamethasone 8 mg IV/PO.
What is the fluid therapy dose for persistent hypotension?
Normal Saline IV (max. 40 mL/kg) titrated to response.
If no consultation is available, what is the repeat fluid dose?
Normal Saline 20 mL/kg IV.
What drug is indicated if poor response to adrenaline and history of heart failure or beta blocker use?
Glucagon 1 mg IV/IM, repeat once at 5 mins if needed.
What adrenaline dose is used in impending cardiac arrest?
Adrenaline 10 mcg IV, escalate to 50–100 mcg IV as needed.
What additional step should be considered in extremely poor perfusion/peri arrest?
Intubation.
What is the definition and pathophysiology for Anaphylaxis
Anaphylaxis is a severe, life-threatening systemic hypersensitivity reaction that occurs rapidly after exposure to an allergen.
It involves airway compromise, breathing difficulty, and/or circulatory collapse and requires immediate treatment with intramuscular adrenaline.
