Anatomy and Physiology Flashcards
(40 cards)
Locus Ceruleus (pons)
Norepinephrine
Ventral tegmentum and SNc (midbrain)
Dopamine
Raphe nucleus (pons, medulla, midbrain)
5-HT
Basal Nucleus of Meynert
ACh
Nucleus Accumbens
GABA
Anxiety NTs
Increased NE
Decreased 5-HT & GABA
Depression NTs
Decreased in NE, DA, 5-HT
Huntington NTs
Increased in DA
Decreased in ACh and GABA
Parkinson NTs
Increased in 5-HT, ACh
Decreased in Dopamine
Alzheimer NTs
Decreased in ACh
Nucleus accumbens and septal nucleus
Reward center, pleasure, addiction, fear
3 Structures in BBB
Tight Junctions b/w nonfenestrated capillary endothelial cells, basement membrane, astrocyte foot processes
Area Postrema
Vomiting after chemo
OVLT
osmotic sensing
Lateral Area of Hypothalamus
Hunger
Destruction = Anorexia, failure to thrive
Ventromedial Area of Hypothalamus
Satiety
Destruction = hyperphagia
Anterior Hypothalamus
Cooling, parasympathetic
Destruction = can’t cool down, too hot
Posterior Hypothalamus
Heating, Sympathetic
Destruction = can’t heat up, too cold
Suprachiasmatic Nucleus
Circadian Rhythm
Tx of bedwetting
oral desmopressin acetate (DDAVP)
Alcohol, Benzodiazepines and barbituates effect on sleep
decreases REM and delta wave
Extraocular movements during REM sleep
PPRF - paramedian pontine reticular formation
Awake eyes open
Beta, highest frequency, lowest amplitude
Awake eyes closed
Alpha