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Pharm Unit 3 Drugs > Anti-anxiety Drugs > Flashcards

Anti-anxiety Drugs Flashcards

1
Q

Misc for Benzodiazepines

A

“Ceiling effect” due to augmenting action of GABA

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2
Q

Diazepam (Valium) Class

A

Benzodiazepine

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3
Q

Clonazepam (Klonopin) Class

A

Benzodiazepine

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4
Q

Lorazepam (Ativan) Class

A

Benzodiazepine

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5
Q

Alprazolam (Xanax) Class

A

Benzodiazepine

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6
Q

Midazolam (Versed) Class

A

Benzodiazepine

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7
Q

Triazolam (Halcion) Class

A

Benzodiazepine

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8
Q

Zolpidem (Ambien) Class

A

Non-benzodiazepine receptor agonist

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9
Q

Flumazenil (Romazicon) Class

A

Benzodiazepine antagonist

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10
Q

Phenobarbitol Class

A

Barbiturate

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11
Q

Diazepam (Valium) MOA

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 43 hours (active metabolites up to 100 hours)

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12
Q

Clonazepam (Klonopin) MOA

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 20-50 hours

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13
Q

Lorazepam (Ativan) MOA

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 14 hours

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14
Q

Alprazolam (Xanax) MOA

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 12 hours

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15
Q

Midazolam (Versed) MOA

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 1.9 hours

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16
Q

Triazolam (Halcion) MOA

A

GABAa agonist; binds between a1 and y2 subunits; half-life of 2.9 hours

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17
Q

Zolpidem (Ambien) MOA

A

BDZ-1 selective agonist

18
Q

Flumazenil (Romazicon) MOA

A

Competitive non-selective antagonist

19
Q

Phenobarbitol MOA

A

GABAa agonist (binds a or b subunit)

20
Q

Buspirone (Buspar) MOA

A

No GABAa interaction; may be partial agonist at 5HT1A

21
Q

Diazepam (Valium) Therapeutics

A

Short-term depression treatment; maintenance of bipolar; severe bipolar; anticonvulsant; muscle relaxant

22
Q

Clonazepam (Klonopin) Therapeutics

A

Short-term depression treatment; maintenance of bipolar; severe bipolar

23
Q

Lorazepam (Ativan) Therapeutics

A

Short-term depression treatment; maintenance of bipolar; severe bipolar; sedation; anticonvulsant; prevent withdrawal symptoms in alcoholics

24
Q

Alprazolam (Xanax) Therapeutics

A

Short-term depression treatment; maintenance of bipolar; severe bipolar; sedation

25
Midazolam (Versed) Therapeutics
Anesthesia (calming effects, production of anterograde amnesia)
26
Triazolam (Halcion) Therapeutics
Short-term depression treatment; maintenance of bipolar; severe bipolar; induce sleep
27
Zolpidem (Ambien) Therapeutics
Sedation and hypnosis without muscle relaxation or anticonvulsant activity
28
Flumazenil (Romazicon) Therapeutics
Benzodiazapine overdose
29
Phenobarbitol Therapeutics
Antiepileptic, anticonvulsant
30
Buspirone (Buspar) Therapeutics
Anxiolytic without marked sedation
31
Diazepam (Valium) SE
Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)
32
Clonazepam (Klonopin) SE
Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)
33
Lorazepam (Ativan) SE
Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)
34
Alprazolam (Xanax) SE
Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)
35
Midazolam (Versed) SE
Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)
36
Triazolam (Halcion) SE
Daytime sedation and drowsiness, anterograde amnesia, synergistic depression of CNS with other drugs, pyschologic and physiologic dependence (chronic use)
37
Zolpidem (Ambien) SE
Sleep-walking; next morning impairment
38
Flumazenil (Romazicon) SE
Withdrawal (may be life-threatening); seizures in mixed overdoses
39
Phenobarbitol SE
Daytime sedation and drowsiness, dose-dependent depression of CNS, pyschologic and physiologic dependence (chronic use)
40
Flumazenil (Romazicon)
Non uniform in reversal of respiratory depression
41
Phenobarbital
Abrupt withdrawal life-threatening

Pharm Unit 3 Drugs (13 decks)

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