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Pharm Unit 3 Drugs > Non-Medical Drugs > Flashcards

Non-Medical Drugs Flashcards

1
Q

Nalmefene (Revex) SE

A

May produce a prolonged withdrawal state (nausea, vomiting, piloerection, yawning)

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2
Q

Nalmefene (Revex) Class

A

Opiod antagonist

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3
Q

N-acetylcysteine (Mucomyst) class

A

Antioxidant

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4
Q

Cocaine class

A

CNS stimulant

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5
Q

LSD class

A

Schedule I Hallucinogen

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6
Q

Mescalineclass

A

Schedule I Hallucinogen

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7
Q

Psilocybin class

A

Schedule I Hallucinogen

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8
Q

Phencyclidine (PCP) class

A

Dissociative anesthetic

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9
Q

Marijuana (THC) class

A

Cannabinoid

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10
Q

Anandamide class

A

Endogenous cannabinoid

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11
Q

Dronabinol (Marinol) class

A

Synthetic THC

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12
Q

Nabilone (Cesamet) class

A

Synthetic THC

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13
Q

N-acetylcysteine (Mucomyst) MOA

A

Supplies sulfhydryl groups to glutathione; improves microcirculation, provides anti-inflammatory effect

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14
Q

Fomepizole (Antizol) MOA

A

Blocks alcohol dehydrogenase

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15
Q

Cocaine MOA

A

Blocks reuptake of dopamine, norepinephrine, and serotonin

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16
Q

LSD MOA

A

Agonist at 5HT2A receptors on Raphe cell body –> inhibition of Raphe Nuclei firing –> increased sensory input; partial dopamine agonist

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17
Q

Mescaline MOA

A

Agonist at 5HT2A receptors on Raphe cell body –> inhibition of Raphe Nuclei firing –> increased sensory input; partial dopamine agonist

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18
Q

Psilocybin MOA

A

Agonist at 5HT2A receptors on Raphe cell body –> inhibition of Raphe Nuclei firing –> increased sensory input; partial dopamine agonist

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19
Q

Phencyclidine (PCP) MOA

A

Antagonist of ion channel associated with NDMA receptor; agonist at mu opioid receptors

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20
Q

Amphetamines (Benzadrine) MOA

A

Indirect sympathomimetic (release biologic amines from nerve terminals in periphery and in CNS); dopamine most important

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21
Q

Marijuana (THC) MOA

A

Hits cannabinoid receptors (CB1, CB2: G-protein coupled receptors)

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22
Q

Anandamide MOA

A

Hits cannabinoid receptors (CB1, CB2: G-protein coupled receptors)

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23
Q

Dronabinol (Marinol) MOA

A

Hits cannabinoid receptors (CB1, CB2: G-protein coupled receptors)

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24
Q

Nabilone (Cesamet) MOA

A

Hits cannabinoid receptors (CB1, CB2: G-protein coupled receptors)

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25
Nalmefene (Revex) Therapeutics
---
26
N-acetylcysteine (Mucomyst) Therapeutics
Acetaminophen overdose
27
Fomepizole (Antizol) Therapeutics
Methanol & ethylene glycol poisoning
28
Cocaine Therapeutics
Topical anesthetic, combined vasoconstrictor and local anesthetic
29
LSD Therapeutics
Schedule I hallucinogen; model hallucinogen against which all others compared; limited studies in psychoanalysis, alcoholism, autistic children, and terminal cancer patients
30
Mescaline Therapeutics
---
31
Psilocybin Therapeutics
---
32
Phencyclidine (PCP) Therapeutics
---
33
Amphetamines (Benzadrine) Therapeutics
Narcolepsy, ADHD
34
Marijuana (THC) Therapeutics
Schedule I hallucinogen; anti-emetic, anti-nausea, and appetite stimulate for cancer chemotherapy and AIDS patients; analgesic for neuropathic pain; potentially: glaucoma, asthma, anxiolytic, migraine, and multiple sclerosis treatment
35
Anandamide Therapeutics
Endogenous cannabinoid
36
Dronabinol (Marinol) Therapeutics
Schedule III drug; anti-emetic, anti-nausea, and appetite stimulate for cancer chemotherapy and AIDS patients
37
Nabilone (Cesamet) Therapeutics
Schedule II drug; treatment-resistant nausea and vomiting, weight loss and anorexia in AIDS patients
38
Nalmefene (Revex) Important SE
---
39
N-acetylcysteine (Mucomyst) Important SE
---
40
Fomepizole (Antizol) Important SE
---
41
Cocaine Important SE
---
42
LSD Important SE
---
43
Mescaline Important SE
---
44
Psilocybin Important SE
---
45
Phencyclidine (PCP) Other SE
Dissociation, confusion, ataxia, marked nystagmus
46
Amphetamines (Benzadrine) Other SE
Tremor, anxiety, irritability, confusion, possibly paranoid state
47
Marijuana (THC) Other SE
May impair reproductive function in adolescents; heavy use may impair development of very young users; possible respiratory damage due to tar
48
Anandamide Important SE
---
49
Dronabinol (Marinol) Important SE
---
50
Nabilone (Cesamet) Important SE
---
51
Nalmefene (Revex) Important SE
---
52
N-acetylcysteine (Mucomyst) Important SE
---
53
Fomepizole (Antizol) Important SE
---
54
Cocaine Important SE
---
55
LSD Important SE
---
56
Mescaline Important SE
---
57
Psilocybin Important SE
---
58
Phencyclidine (PCP) Other SE
Dissociation, confusion, ataxia, marked nystagmus
59
Amphetamines (Benzadrine) Other SE
Tremor, anxiety, irritability, confusion, possibly paranoid state
60
Marijuana (THC) Other SE
May impair reproductive function in adolescents; heavy use may impair development of very young users; possible respiratory damage due to tar
61
Anandamide Important SE
---
62
Dronabinol (Marinol) Important SE
---
63
Nabilone (Cesamet) Important SE
---
64
Nalmefene (Revex) Misc
---
65
N-acetylcysteine (Mucomyst) Misc
---
66
Fomepizole (Antizol) Misc
Very expensive
67
Cocaine Misc
Rapidly hydrolyzed by plasma cholinesterase; crack is the free base form
68
LSD Misc
Oxidized in liver; cross tolerance with mescaline and psilocybin
69
Mescaline Misc
Cross tolerance with LSD and psilocybin
70
Psilocybin Misc
Cross tolerance with mescaline and LSD
71
Phencyclidine (PCP) Misc
Long half-life due to being highly lipid soluble and having active metabolites
72
Amphetamines (Benzadrine) Misc
Others: dextroamphetamine (Dexedrine), methamphetamine (Desoxyn), methylphenidate (Ritalin)
73
Marijuana (THC) Misc
Active ingredient is delta-9-tetrahydrocannabinol; metabolized by P450, with chronic use inducing enzyme; highly lipid soluble
74
Anandamide Misc
---
75
Dronabinol (Marinol) Misc
---
76
Nabilone (Cesamet) Misc
Less psychoactive side effects than marijuana

Pharm Unit 3 Drugs (13 decks)

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