Flashcards in Antibiotic therapy cases Deck (26):
Strep throat is caused by;
Group A strep
Bacterial pharyngitis is caused by;
Group A strep
What type of B-lactam is amoxicillin?
What addition to the B-lactam ring in aminopenicillins makes them able to enter porins?
R side chain
What are ampicillin and amoxicillin effective against?
Gram-negatives (especially rods)
What is the spectrum of a activity for aminopenicillins?
E. coli, Shigella, Salmonella enterica, borrelia burgdorferi, and most strep species (GAS, GBS, viridans group)
What are the beta-lacatmase inhibitors?
What bacteria have B-lactamases?
What are the anti-stap penicillins?
What are the anti-staph pencillins active against?
MSSA (methicillin sensitive staph aureus
MSSE (methicillin sensitive staph epidermidis)
What are the anti-staph pencillins not active against?
MRSA and MRSE
How do anti-staph penicillins avoid B-lactamases?
Large R side group that makes them resistant to the enzyme
What bacteria generally causes bacterial cystitis?
what is the most common cause of pharyngitis?
what is the most common bacterial cause of cystitis?
what antibiotic is normally used for gram negative bacteria but can be given with penicillin for synergy in the treatment of subacute endocarditis?
What antibiotic regimen is recommended for empiric treatment of community acquired pneumonia?
ceftriaxone plus azithromycin
what anaerobe is most likely involved in sepsis following a ruptured appendix?
What is recommended for N. Gonorrheae?
MRSA is resistant to beta lactam antibiotics through which mechanism?
mutation of the transpeptidase
What antibiotic would be least likely to be used to treat a Pseudomonas infection?
What can treat a Pseudomonas infection?
Extended spectrum penicillins (piperacillin, ticarcillin)
Cephalosporins 3rd and 4th gen (ceftazidime, cefepime)
Carbapenems (Imipenem, meropenem)
Quinolones (cipro, levofloxacin)
Aminoglycosides (gentamycin, tobramycin, amikacin)
How would an infection of Mycobacterium tuberculosis be treated?
4 drug cocktail: RIPE
What are some antibiotics used for a group A step infection?
Aerobic gram neg