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Flashcards in Antibiotic therapy cases Deck (26):
1

Strep throat is caused by;

Group A strep

2

Bacterial pharyngitis is caused by;

Group A strep

3

What type of B-lactam is amoxicillin?

Aminopenicillin

4

What addition to the B-lactam ring in aminopenicillins makes them able to enter porins?

R side chain

5

What are ampicillin and amoxicillin effective against?

Gram-negatives (especially rods)

6

What is the spectrum of a activity for aminopenicillins?

E. coli, Shigella, Salmonella enterica, borrelia burgdorferi, and most strep species (GAS, GBS, viridans group)

7

What are the beta-lacatmase inhibitors?

Clavulanic acid
Sulbactam
Tazobactam

8

What bacteria have B-lactamases?

Staph aureus
H. Influenzae
N. gonorrhoeae
Enterbacteriaceae
Some anaerobes

9

What are the anti-stap penicillins?

Nafcillin
Ocacillin
Dicloxacillin

10

What are the anti-staph pencillins active against?

MSSA (methicillin sensitive staph aureus
MSSE (methicillin sensitive staph epidermidis)

11

What are the anti-staph pencillins not active against?

MRSA and MRSE

12

How do anti-staph penicillins avoid B-lactamases?

Large R side group that makes them resistant to the enzyme

13

What bacteria generally causes bacterial cystitis?

E. coli

14

what is the most common cause of pharyngitis?

GAS

15

what is the most common bacterial cause of cystitis?

E. Coli

16

what antibiotic is normally used for gram negative bacteria but can be given with penicillin for synergy in the treatment of subacute endocarditis?

Gentamycin

17

What antibiotic regimen is recommended for empiric treatment of community acquired pneumonia?

ceftriaxone plus azithromycin

18

what anaerobe is most likely involved in sepsis following a ruptured appendix?

Bacteriodes

19

What is recommended for N. Gonorrheae?

Ceftriaxone

20

MRSA is resistant to beta lactam antibiotics through which mechanism?

mutation of the transpeptidase

21

What antibiotic would be least likely to be used to treat a Pseudomonas infection?

Cefazolin

22

What can treat a Pseudomonas infection?

Extended spectrum penicillins (piperacillin, ticarcillin)
Cephalosporins 3rd and 4th gen (ceftazidime, cefepime)
Carbapenems (Imipenem, meropenem)
Aztreonam
Quinolones (cipro, levofloxacin)
Aminoglycosides (gentamycin, tobramycin, amikacin)
Combination therapy

23

How would an infection of Mycobacterium tuberculosis be treated?

4 drug cocktail: RIPE
Isoniazid
Rifampin
Ethambutol
Pyrasinaminde

24

What are some antibiotics used for a group A step infection?

Amoxicilin

25

Aerobic gram neg

Gentamycin

26

Can Mtb be isoniazid resistant?

yes