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Flashcards in Antibiotics I Deck (31):
1

What are 3rd generation cephalosporins used to treat?

Some gram + more so gram - cocci

2

Aminoglycosides:

Streptomycin

Kanamycin

Neomycin

Gentamicin

Amikacin

3

What are the two general categories of DNA topoisomerases?

Quinolones

Fluoroquinolones

4

Miscellaneous cell wall inhibitors:

Bacitracin

5

What are 2nd generation cephalosporins used to treat?

Gram + cocci and some gram -

6

Tetracyclines:

Doxycycline

Minocycline

Tetracycline

7

What are penicillin 1st generation drugs?

Benzyl penicillin (oral) Penicillin V (oral)

8

Two categories of 50s ribosomal subunit binders:

Macrolides

Chloramphenicol

Lincosides

9

What are the narrow spectrum penicillinase-resistant penicillins?

Dicloxacillin Oxacillin Nafcillin Methicillin

10

What are the 4th generation cephalosporins?

Cephepine

11

What are broad-spectrum penicillinase sensitive drugs?

Ampicillin Amoxicillin Pipericillin

12

Two categories of 30s ribosomal subunit inhibitors:

Aminoglycosides (bacteriocidal)

Tetracyclines (bacteriostatic)

13

Chloramphenicol:

Chloramphenicol

14

What are the two general bacterial protein synthesis inhibitors?

30s ribosomal subunit inhibitors 50s ribosomal subunit inhibitors

15

Macrolides:

Azithromycin

Clindamycin

Erythromycin

16

What are 4th generation cephalosporins used to treat?

Gram + cocci and gram - cocci 

17

What are the two general categories of anti-folate drugs?

Sulfanamides

Dihydrofolate reductase inhibitors

18

Three types of penicillins?

Narrow spectrum - penicillinase-sensitive Narrow spectrum - penicillinase-resistant Broad spectrum - penicillinase-sensitive

19

How do penicillins work?

Covalently bond and inactivate penicillin bind protein (peptidase forming a cross link in the cells wall)

20

What are the 2nd generation cephalosporins?

Cefoxitin 

21

What are the 3rd generation cephalosporins?

Cefteriaxone

22

Carbapenem antibiotic

Imipenem

23

Glycopeptide antibiotic:

Vancomycin

24

Fluoroquinolones:

Ciprofloxacin

Levofloxacin

25

What are non-beta-lactam cell wall inhibitors?

Miscellaneous cell wall inhibitors Glycopeptide antibiotics

26

What are 1st generation cephalosporins used to treat?

Gram + cocci

27

What are the beta-lactam (cell wall synthesis inhibitors) antibiotics?

Penicillins Cephalosporins Carbapenems Monobactams

28

What are the 1st generation cephalosporins?

Cephazolin

Cephalexin

29

Lincosides:

Clindamycin

30

Monobactam antibiotic:

Aztreonam

31

DHFR inhibitors:

TMP

Pirymethamine