[anticoagulants] Flashcards
(34 cards)
1
Q
A
LMWH
unfractionated
2
Q
A
SC
3
Q
A
Factor Xa
4
Q
A
LMWH
5
Q
A
LMWH
6
Q
A
-parin
7
Q
A
dalteparin
enoxeparin
8
Q
A
binds to antithrombin 3 and potentiates it
AT3 inhibits thrombin, Xa and IXa
9
Q
A
rapid
10
Q
A
LMWH
11
Q
A
HIT
heparin induced thrombocytopenia
12
Q
A
previous HIT bleeding disorders peptic ulcer cerebral haemorrhage severe hypertension neurosurgery
13
Q
A
PO
14
Q
A
inhibits reductase enzyme responsible for activating vit K
15
Q
A
YES
16
Q
A
warfarin
17
Q
A
Xa inhibitor
18
Q
A
LMWH
Fondaparinux
19
Q
A
5 days
OR
until INR reached
(whichever is longer)
20
Q
A
warfarin has an initial prothrombotic effect
21
Q
A
6 weeks below knee
3 months above knee
22
Q
A
unprovoked DVT
i.e. no surgery/immobility
23
Q
A
1.5 - 2.5
24
Q
A
LMWH given for 6 months
25
[anticoagulants]: VTE Tx: what is the target INR for warfarin treatment for a patient with DVT/PE/atrial fib/stroke prevention
2 - 3
26
[anticoagulants]: VTE Tx: what is the target INR for warfarin treatment for a patient with recurrent DVT/PE
3.5
27
[anticoagulants]: VTE Tx: what is the target INR for warfarin treatment for a patient with prosthetic heart valves
3-4
28
[anticoagulants]: VTE Tx: warfarin Tx is usually for 3 months; what indication is there for indefinite warfarin Tx
enduring cases e.g. thombophilia
29
[anticoagulants]: VTE Tx: above what INR should warfarin be stopped (and started when INR falls below this level)
>5
30
[anticoagulants]: VTE Tx: if there is a major bleed (e.g. intracranial haemorrhage) what overdoes Tx is there for warfarin (2)
prothrombin complex
Vit K IV
(FFP if vit k too slow)
31
[anticoagulants]: VTE Tx: what is the 1st dose of warfarin Tx
10mg
32
[anticoagulants]: VTE Tx: what is the 2nd dose of warfarin Tx (2)
5mg (if >60, cardiac, liver disease)
| 10mg
33
[anticoagulants]: VTE Tx: how can you reverse the effects of LMWH/UFH if there is bleeding
protamine sulphate
34
[anticoagulants]: VTE Tx: how does protamine sulphate work
binds to heparin and inactivates it
