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HAEMATOLOGY > [CML] > Flashcards

Flashcards in [CML] Deck (24)
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1
Q
A

myeloproliferative disorder

2
Q
A

4

3
Q
A

Philadelphia Ch. +

Philadelphia Ch. -

4
Q
A

CML

5
Q
A

Polycythaemia vera
Essential thrombocytosis
Myelofibrosis

6
Q
A

rarely

7
Q
A

Philadelphia Chr.

8
Q
A

t(9:22)

t=translocation

9
Q
A

BCR:Abl

10
Q
A

worse

11
Q
A

massive spenomegaly
hepatomegaly
bruising (platelet dysfunction)

12
Q
A

chronic/insidious

13
Q
A

weight loss
sweats
fever
tired

14
Q
A

Raised (>100x10^9/L)

15
Q
A

hypercellularity

16
Q
A

yes (all myeloid line)

17
Q
A

chronic
accelerated
blast transformation

18
Q
A

chronic

19
Q
A

blast transformation

20
Q
A

BCR:Abl gene tyrosine receptor

21
Q
A

imatinib

Nilotinib

22
Q
A

allogenic HLA matched stem cell transplant

23
Q
A

young patients (if risk low)

24
Q
A

Older patients