Anticoagulation Flashcards
(24 cards)
Hemostatsis is
the process of forming a blood clot (clotting for bleeding)
coagulation is?
the steps of forming a blood clot
thrombus is?
a blood clot that STAYS in one place
embolus is a ?
blood clot that MOVES thru blood vessels
thrombus and embolus can become?
each other
tissue plasminogen activtor is?
natural blood clot dissolver (to keep balance)
-proteins
coagulation cascade
series of steps of proteins–> becoming other proteins–> into blood clot
what is fibrin?
the last step before blood clot
-actual protein blood clot
what is fibrinolysis?
the process of breaking down blood clot
what is plasminogen?
a protein that breaks down blood clot(s)
what is plasmin?
protein that breaks down blood clot(s)
extrinsic pathway needs?
Calcium to blood clot
-Fibrin is the actual blood clot
what helps fibrin make itself?
prothrombin–> fibrinogen–> fibrin–> blood clot
extrinsic pathway occurs?
OUTSIDE factor (ex: needle, car crash, gun shot wound)
intrinsic pathway occurs?
injury INSIDE to out body
You need what mineral to blood clot?
calcium
fibrinogen makes?
ACTUAL blood clot (fibrin)
what causes intrinsic pathway injury?
hypertension
pathway for intrinsic pathway injury?
HTN injury–>dent in blood vessel–> covers putty (Cholesterol)–> build up of cells–> plaque–> rupture–> MI or stroke
Fibrinolysis pathway?
plasminogen becomes plasmin
what does plasmin do?
—> TEARS blood blots
thromboembolic evets example?
MI–> blood clot in heart
cerebrovasular accident (CVA): blood clot in brain
Pulmonary embolism (PE): blood clot in lungs
DVT: blood clot in leg
S&S of PE?
chest pain, cough, dyspnea, hemoptysis (cough blood)
S&S of DVT?
calf edema, pain, warm and redness,
