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Nursing 2P16 > Antiemetic > Flashcards

Flashcards in Antiemetic Deck (32):
1

dolasetron trade name

anzemet

2

dolasetron expected effect

prevent nausea, vomit by blocking it in small intestine

3

why use dolasetron

prevent postop nausea and vomit

4

dolasetron route admin

IV PO

5

dolasetron adverse effects

dysrhythmias, ventricular tachycardia/ fibrillation, QT prolongation, cariac arrest, bronchospasm

6

dolasetron doses

IV 12.5mg before start anesthesia
PO 100mg 2h before surgery

7

dolasetron nursing implications

assess: hypersensitivity, cardiac conduction, electrolyte imbalances, dysrhythmias
evaluate: therapeutic response
teach: report typical side effect problems
may cause headache so use anagesic

8

dimenhydrinate trade names

dramamine, driminate, gravol

9

dimenhydrinate classes

antiemetic, antihistamine, anticholinergic

10

dimenhydrinate why use

motion sickness, nausea, vomit, vertigo

11

dimenhydrinate expected effect

compete with histamine for H1 receptors in GI, blood, rest tract; anticholinergic, less vestibular sim, block chemoreceptor trigger

12

dimenhydrinate dose

PO 50-100 q4h
IM IV 50mg q4h

13

dimenhydrinate route admin

PO IM IV elixir

14

dimenhydrinate adverse effects

ANAPHYLAXIS, dry mouth, drowsy, dry mouth, hypotension, constipation

15

dimenhydrinate nursing implications

check BP, vitals,
signs toxicity mask symptoms of disease
avoid hazards/ alert activities
avoid alcohol depressants

16

meclizine trade names

antivert, bonine, dramamine less drowsy formula

17

meclizine class

antiemetic, antihistamine, anticholinergic

18

meclizine expected effect

act centrally by blocking chemo zone which acts on vomit centre

19

meclizine why use

vertigo, motion sickness

20

meclizine route admin

PO

21

meclizine doses

vertigo: 25-100mg
motion sickness: 25-50mg 1h before travelling

22

meclizine adverse effects

ANAPHYLAXIS, drowsy, urine retention, hypotension, constipation, blurred vision

23

meclizine nursing implications

alert: signs toxicity other products mask symptoms disease
may cause false positive allergy
avoid alcohol, depressants, no breast feeding

24

metoclopramide trade names

Apo-metoclop, metozolv, reglan

25

metoclopramide drug classes

antiemetic, cholinergic

26

metoclopramide expected effect

contract gastric muscle in upper GI tract by enhancing tissues response to ACh, relax pyloric & duodenal segments, increase peristalsis without stimulating secretions & block dopamine in chemo trigger zone in CNS

27

why use metoclopramide

prevent nausea, vomit from chemo, radiation, delayed gastric emptying, GERD

28

metoclopramide route admin

PO IV

29

metoclopramide adverse effects

sucide, neuroleptic malignant, tardive dyskinesia, penias

30

metoclopramide doses

nausea vomit: 1-2mg/kg IV 30 min befor chemo, q2h x 2 doses then q3h x 3 doses

GERD
PO 10-15 mg qid 30 mins before meals and bed

diabetic gastroparesis
PO 10mg 30min before meals, at bed x 2-8 wk

31

metoclopramide black box warning

EPS, tardive dyskinesia

32

metoclopramide nursing implications

neuroleptic malignant syndrome, avoid driving & hazardous activities, avoid alcohol & CNS depressants