Proton Pump Inhibitors Flashcards Preview

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Flashcards in Proton Pump Inhibitors Deck (16):
1

Pantoprazole trade names

Panto, Pantoloc, Protonix, Protonix IV, Tecta

2

Pantoprazole drug classification

proton pump inhibitor

3

pantoprazole expected effect

suppress gastric secretions by inhibiting H/K ATPase enzyme system in gastric parietal cell. Gastric acid inhibitor bc blocks final step of acid production

4

why use pantoprazole

GERD, severe erosive esophagitis, pathologic hypersecretion (Zollinger- Ellison)

5

pantoprazole adverse effects

headache, insomnia, fatigue
diarrhea, abdominal pain, flatulence
myalgia, rhabdomyolysis
Stevems Johnson syndrome, toxic epidermal necrolysis, angioedema
weight gain/ loss, hyperglycemia

6

pantoprazole route of admin

PO, NG, IV

7

pantoprazole nursing implications

- watch for hypersensitivity
- serious skin disorders
- precaution for breast feeding, pregnant, children
- rhabdomyolysis (muscle pain, ^ CPK)

8

pantoprazole dosages

GERD PO 40mg/ day
erosive esophagitis IV & PO 40mg/day
hypersecretory conditions PO 40mg BID, IV 80mg q12h, max 240mg/day
ulcers 40mg BID

9

omeprazole trade names

Losec, Prilosec

10

omeprazole drug classification

proton pump inhibitor

11

omeprazole expected effect

suppress gastric secretion by inhibiting H/K ATPase enzyme in gastric parietal cells, Blocks final step acid production

12

omeprazole why use

GERD, erosive esophagitis, hypersecretory conditions (Zollinger- Ellison), mastocytosis, duodenal ulcers

13

omeprazole route of admin

PO, NG

14

omeprazole dosages

GERD/ erosive esophagitis 20mg/ day PO
hypersecretory conditions 60mg/ day, up to 120mg, no single dose over 80mg
duodenal ulcer 20mg daily, 40mg if H Pylori
gastric ulcer 40mg/ day

15

omeprazole adverse effects

LIFE THREATENING hepatic failure & pneumonia

16

omeprazole nursing implications

precaution: children, pregnancy
GI: bowel sounds, pain, swelling
electrolyte imbalance
hepatic enzymes (CBC, vitamin B12)
CBC
discontinue if black tarry stools, abdominal cramps