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CNS I > anxiety disorders > Flashcards

anxiety disorders Flashcards

At the end of the learning, students will be able to do the following regarding the anxiety disorders: Describe basic neuroanatomy and neurophysiology Choose the correct diagnosis from a vignette List important medical and psychiatric disorders in the differential diagnosis State important comorbidities and how they alter treatment Identify the correct pharmacologic and psycholotherapeutic treatments (52 cards)

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1
Q

the instincual fear center

A

amygdala

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2
Q

is hyperactive in most anxiety disorders

A

hyperactive

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3
Q

NT involved in anxiety disorder

A

NE

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4
Q

NE released from

A

Locus Ceruleus

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5
Q

Locus Ceruleus located in the

A

Pons

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6
Q

gender distribution of anxiety disorders

A

2x females as males (except OCD)

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7
Q

DOC for anxiety disorders

A

SSRI

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8
Q

6 SSRIs

A

Sertaline, paroxetine, fluoxetine, fluvoxamine, citalopram, escitalopram

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9
Q

MOA of SSRI in Anxiety disorder

A

reducing locus ceruleus firing with chronic use

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10
Q

effective non-drug therapy for anxiety disorder

A

CBT

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11
Q

frequent co-morbidity in anxiety disorders

A

EtOH use disorder (self medication)

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12
Q

why does Alcohol seem to work in anxiety

A

GABAergeneric properties of EtOH

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13
Q

CBT most effective in anxiety when

A

meds are started first

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14
Q

works on faulty/distorted thoughts

A

cognitive therapy

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15
Q

works on breathing, relaxation, and graduated exposure

A

behavioral therapy

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16
Q

age of onset of panic disorders

A

20s

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17
Q

influx of ____(3) in PD pts can trigger panic attacks

A

CO2, sodium lactate, or bicarb

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18
Q

DX criteria for Panic Disorder

A

1) recurrent unexpected attacks
2) at least one attack has been followed by a month or more of persistant worry/change in behavior regarding the attacks
3) not another axis 1 or due to substances/other medical condition

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19
Q

sx of panic attacks

A

4 or more:
palp, chest pain, sweating, trembling, SOB, nausea, syncope, derealization/depersonalization, fear of going crazy.dying, numbness/tingling, chills/hotflashes

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20
Q

medical disorders to rule out in panic disorder

A

caffeine OD, heart/lung/thyroid disease, drug use

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21
Q

major ddx when panic disorder onsets later in life

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A

heart/lung problems

22
Q

95% of people with this, have PD

23
Q

associated with worse prognosis of PD

24
Q

mainstay of PD treatment

25
possiblly effective in PD, but associated with severe side effects
MAOI
26
used in emergent PD situations
benzo
27
General Anxiety disorder dx criteria
excessive anxiety and worry, more days than not dor at least 6 months 3 or more of: restlessness/keyed up/on edge, easy fatigue, difficulty concentrating, irritaility, muscle tension, sleep disturbance not another axis 1 causes distress/impairment
28
somatic sx of GAD
GI troubles, headaches, insomnia, palpitations, muscle tension and aches, SOB/dyspnea, loss of libido
29
major comorbidity with GAD
major Depression
30
overlapping sx of MDD and GAD
anxiety, sleep problems, psychomotor agitation, dfficulty concentrating, irritabiliy, fatigue
31
DOC for GAD
SSRI
32
particular SSRI approved for GAD
paroxetine/venlafaxine
33
buspirone effective for
GAD
34
most common comorbidity to OCD
tourette's
35
ego dystonia
knowing that the behavior is abnormal
36
OCD is (dystonic/syntonic)
dystonic
37
anxiety disorder more common to adult women
OCD
38
age when OCD is more common in males
adolescence
39
age of onset of OCD
20s, rare in age 35
40
66% of people with _____ have OCD
tourette's
41
PET shows increased activity of the (3)____ in OCD
orbotofrontal, ACC and caudate
42
circuit abnormality in OCD
orbitofrontal-limbic-basal ganglia
43
dx criteria of OCD
precense of either obsesions or compulsions that caue distress or are disabling
44
type of CBT in OCD
exposure-response prevention
45
DOC (current) in OCD
SSRI
46
old drug in OCD
clomipramine
47
drug used in tourette's+OCD or in refractory OCD
risperidone
48
DX criteria in Social anxiety disorder (SAD)
fear of humilation of embarrassment to social sitations
49
DOC in SAD
SSRI (possible MAOI and Benzo)
50
drug for situational type of SAD
propanolol
51
DOC for specific sphobia
SSRI
52
best treatment for specific phobia
systematic desensitivation

CNS I (36 decks)

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