Bipolar Flashcards

• Describe a manic episode and differentiate it from hypomania or a primary psychotic episode • Differentiate between Bipolar I, Bipolar II and Cyclothymia • List common medications, medical conditions and environmental changes associated with mania

1
Q

age of onset in bipolar

A

20s

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2
Q

more severe bipolar (1/2)

A

2

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3
Q

prevalance of bipolar

A

1% lifetime prevalence

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4
Q

gender distribution in biolar

A

equal in I, more females in II

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5
Q

define hypomania

A

manic sx without psychotic sx

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6
Q

predictor of poor outcome in bipolar

A

psychotic mania

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7
Q

worsens the course of Bipolar

A

substance abuse

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8
Q

causes of mania after age 40

A

drugs, steroids, brain trauma, HIV, stroke, MS, epilepsy, tumor

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9
Q

precipitants for mania (7)

A

post-partum state, sleep deprivation, dopamine agonists, antidepressents, stroke/brain injury, jet lag, severe stress

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10
Q

hypomaniac pts are diagnosed with what type of bipolar

A

II

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11
Q

do pts know they are having a manic episode?

A

no, usually the behaviour is brought to their attention

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12
Q

rapid cycling definition

A

4 or more mood episodes a year

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13
Q

define dysphoric mania

A

depression and mania smultaniously

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14
Q

more common: depression or mania

A

depression

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15
Q

more likely to be depressed: bipolar 1 or 2

A

2

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16
Q

more likely to be asymptomatic at any given time, 1 or 2

17
Q

possible first sign of bipolar in teens

A

atypical depression

18
Q

may result from Li+ use

A

hypothyroidism

19
Q

can mimic depression

A

hypothyroidism

20
Q

risk of antidepressents in bipolar

A

can bring about manic episode

21
Q

definition of cyclothymia

A

2 years of hypomania and numerous periods of depressive sx that do not meet criteria for major depression

22
Q

chance of a bipolar pt having substance addiction

23
Q

manic sx

A

inflated self esteem, decreased need for sleep, distractability, rapid speech, racing thoughts, increased goal directed behavior, excessive involvement in pleasurable activites

24
Q

acroym for manic sx

25
DIGFAST
``` distractable increased activity grandiosity flight of ideas (racing thoughts) activites that are dangerous or hypersexuality sleep decreased talkative speech ```
26
definition of bipolar 1
manic episode, with or without episode of major depression
27
definition of bipolar 2
major depression and hypomania
28
dx criteria of bipolar 1
one manic episode (because 90% are going to have a depressive episode at some point(
29
dx criteria of bipolar 2
hypomania and an episode of major depression
30
distinguishes schizophrenia from bipolar
schizophrenia thoughts are mopre fragmented and bizzare with less intense affect
31
areas in the brain effected by bipolar
PFC, Ventrat tegmental area, periaqueductal grey matter, basal ganglia
32
define kindling in bipolar
idea that each episode makes it easier to have a subsequent episode
33
3 bipolar classic mood stabilizers
lithium, valproic acid, carbamazepine
34
6 2nd gen mood stabilizers
aripirazole, quetiapine, risperidone, ziprasidone, olanzapine
35
drug combo for bipolar depression
fluoxetine-olanzaoine
36
serious condition that lamotrigrine can cause
steven-johnson syndrome
37
appoved for maintaince in bipolar
lamotrigine