Anxiolytics and Antidepressants Flashcards Preview

Year 2 Pharmacology > Anxiolytics and Antidepressants > Flashcards

Flashcards in Anxiolytics and Antidepressants Deck (23):
1

Antidepressants

MAOIs
Tricylic drugs
SSRIs
Lithium

2

Anxiolytics

Sedative-hypnotics
Benzodiazepines
Second generation non-benzodiazepines

3

Antipsychotics

Neuroleptics
Atypical drugs

4

The classic tricyclic antidepressant drugs inhibit..

both serotonin and noradrenaline reuptake into nerve terminals

5

Examples of Monoamine oxidase inhibitors (MAOIs)

Phenetzine - D+Bipolar
Tranylcypromin - severe depression

"cheese effect" Inhibition of cytochrome P450

6

What do MAOIs do?

non-selective blockers of the metabolism of all monaines

7

Side effects of MAOIs

Weight gain
Oedema
Sexual dysfunction
Sedation

8

Examples of Tacyclic anti-depressants

Imipramine - D
Amitripityline - D
Doxepin - Anxiety

9

What are Tacyclic anti-depressants used for

Major depressive episodes
Panic disorders
OCD

10

Caution and side effects of tacyclic anti-depressants

Caution : Pts with MI, coronary instability, avoid CNS depressants

Side effects : weight gain
sexual dysfunction
inhibition of cytochrome p450
sedation
dry mouth
blurred vision
constipation

11

Examples of Selective Serotonin Reuptake Inhibitors (SSRIs)

Fluoxetine - D + OCD
Paroxetine - D + Panic
Sertraline - D + Panic
Citalopram - D

12

Side effects of SSRIs

Sexual dysfunction
dependence and withdrawal

Inhibit serotonin uptake
Inhibit reuptake of noradrenaline and serotonin

13

Other examples of antidepressants

Bupropion - D
Venlafazine - D

14

Example of Sedative Hypnotics (Anxiety)

all make you sleep

Thiopental - prep for surgery
Secobarbital
Phenobarbital
Zolpidem

Treatment for insomnia, anxiety, agitation, seizures

15

Side effect of sedative hypnotics

suicidal thoughts

16

Examples of Benzodiazepines (Anxiety)

'PAM'

Diazepam
Alprazolam
Tenazepam
Lorazepam

17

Side effects for non-benz / benzodiazepines

headache
dry mouth
blurred vision
ddizziness
memory loss
hypotension

18

Example of Non-benzodiazepines

Baspirone

19

Two types of drugs to treat psychosis

Antipsychotic / neuroleptics
Atypical antipsychotics

20

Examples of Antipsychotic / neuroleptics

Chlorpromazine
Fluphenazine
Haloperodol
Loxapine

21

Side effects of Antipsychotic / neuroleptics

Parkinsonism
Tardive dyskinesia
Hypotension
Sedation
Thermoregulation probs

22

Examples of atypical antipsychotics

Clozapine
Amisulpride
Rispendone
Olanzepine

23

Side effects of atypical antipsychotics

Photosensitivity
Headache
Blurred vision
GI probs
Dizziness
Insomnia