Ischaemic Insult Flashcards Preview

Year 2 Pharmacology > Ischaemic Insult > Flashcards

Flashcards in Ischaemic Insult Deck (18):
1

Alteplase

Thrombolytic agent
Recombinant human proteins

2

Aspirin

NASID - Antiplatelet
-inhibits cyclooxygenase
-prevents thromboxane formation

3

Dipyridamole

Antiplatelet
-inhibits thromboxane synthesis
-prevent thromboxane formation

4

Clopidogrel

Antiplatelet
-antagonize actions of ADP at purinergic receptors

5

Abciximab

Antiplatelet
- prevents linking of platelet to fibres

6

Heparin

Anticoagulant
-anti thrombin
-activated body's own anti-clotting molecules

7

Warfarin

Anticoagulant
Inhibition of vit K reductase
Acts on liver to inhibit the enzyme vit k reductase
Diminishes clotting factors
Stops body being able to make enough fibrin

8

Side effects of Warfarin

V complex metabolism
Changes with diet, drinking and acute illness

9

Apirin
Dipyridamole
Clopidogrel
Abciximab
are examples of

Antiplatelet drugs

10

Antithrombin
Heparin
Warfarin
are examples of

Anticoagulants

11

Alteplase
Streptokinase
Urokinase
are examples of

Thrombolytic agents

12

Bivalirudin
Lepirudin

Thrombin inhibitors

13

Protamine sulphate
Vit K

are example of

Anticoagulant therapy

14

Dalteparin

Low-molecular-weigh heparins

15

Systemic Haemostatic Agents

Aprotinin

16

Clot busting, short acting
risk: intracerebral haemorrhage

thrombin/fibrinolytic drugs

17

inhibit platelet aggregation/thrombus formation

antiplatelet drugs

18

inhibit production of Vit K

anticoagulants