Radiotherapy Flashcards Preview

Year 2 Pharmacology > Radiotherapy > Flashcards

Flashcards in Radiotherapy Deck (14):
1

What is radiotherapy?

Treatment of disease by ionising radiation

2

What does radiotherapy do?

Penetrates tissues and alter the nuclear material, ie, DNA disrupting cell growth and reproduction

Damaging human cells causing apoptosis
Targets damaged cancer cells

3

Alpha and gamma radiation

Increase of tissue damage
As it is more effective and powerful

4

Uses of radiotherapy are

Treat cancer
Shrink cancer
Reduce cancer
Control symptoms/ reduce pain
Reduce growth

5

External radiotherapy

Given over 7 days
Mark targeted on body
Pts lays for 5mins and painless

6

Conformal radiotherapy CRT

Routinely for prostate cancer

7

Internal radiotherapy

Radioactive
Wires
Seeds (perm)
IV or liquid
Short stay in hosp

8

IV/ liquid internal

Strontium 89
Samarium 153
Iodine
Radium

9

Effects of radiotherapy

Damage to healthy cells
Dependent on area
Dose of radiation
Psychical well being at the time

Tiredness = anaemia
Bone marrow effect
Diarrhoea
Less 02 carrying

N+V= prescribe anti emetic, anti his, antag

Sore skin
Hair loss
Muscle and joint pain
Fertility

10

Radiotherapy and the thyroid gland

Graves' disease
Decrease activity of TG by destroying cells
Less t3 t4 release

11

Future radiation

Hypofraction
Hyperfraction

12

Hyper fraction radiation

High freq of fractions more in one day
12 days rather than 4-6 weeks

13

Hypo fraction radiation

Decrease in total amount of radiotherapy received

Assess reeducation in side effects and reduction in risk of recurrence of the cancer

14

Stereotactic radiotherapy

Treat small brain tumours