Anxiolytics, Hypnotics, Antidepressants, Neuroleptics and Drugs of Abuse

Question 1

SSRI’s are a class of _

Answer 1

Antidepressants

Question 2

True/False: Caffeine is a bronchodilator

Answer 2

TRUE- Caffeine is a bronchodilator

Question 3

Ethanol is a _, _, and _, depressant?

Answer 3

Myocardial
Respiratory
CNS

Question 4

True/False: Methamphetamine increases DA release

Answer 4

TRUE

Question 5

True/False: Neuroleptics can be used as antiemetic agents

Answer 5

TRUE

Question 6

How do SSRI’s work?

Answer 6

SSRI’s block the reuptake of 5-HT, making more 5-HT available

Question 7

Fluoxetine (Prozac) is in a class of _ called _

Answer 7

Antidepressants, SSRI’s

Question 8

The Biogenic Amine Theory explains depression with _

Answer 8

a deficiency in biogenic amines NE or 5-HT

Question 9

Side effects of SSRI’s include…

Answer 9

reduced libido, affected appetite, and possibly seratonin syndrome.

Question 10

Amitriptyline (Elavil) is in a class of _ called _

Answer 10

Antidepressants, TCA’s

Question 11

How do TCA’s work?

Answer 11

TCA’s block the reuptake of 5-HT and NE, making more 5-HT and NE available

Question 12

Side effects of TCA’s include…

Answer 12

anticholinergic side effects, drowsiness, hypotension, and a1 blockade.

Question 13

TCA’s are a class of _

Answer 13

Antidepressant

Question 14

MAOI’s are a class of _

Answer 14

Antidepressant

Question 15

Low dose manifestations of nicotine does what to the autonomic nervous system?

Answer 15

Stimulates autonomic ganglia, increasing sympathetic and parasympathetic divisions

Question 16

High dose manifestations of nicotine does what to the autonomic nervous system?

Answer 16

Causes ganglionic blockade, shutting down autonomic nervous system

Question 17

How does ethanol exacerbate ulcer problems?

Answer 17

Increases HCl secretion

Question 18

True/False: Ethanol is a vasodilator

Answer 18

TRUE- Ethanol is a cutaneous vasodilator

Question 19

How does cocaine cause euphoria?

Answer 19

Blocks NE, DA, 5-HT reuptake

Question 20

How can cocaine cause psychosis?

Answer 20

Cocaine reduces reuptake of DA, leading to excessive DA, which is associated with psychosis.

Question 21

True/False: Cocaine is a vasoconstrictor

Answer 21

TRUE- Cocaine is a vasoconstrictor

Question 22

Excessive DA is associated with _

Answer 22

Psychosis

Question 23

Two DA pathways of the CNS:

Answer 23

Nigrostriatal + Mesolimbic Pathway

Question 24

The nigrostriatal pathway is associated with

Answer 24

Voluntary motor control

Question 25

The mesolimbic pathway is associated with

Answer 25

Regulation of behavior and emotion

Question 26

DA deficiency is associated with _

Answer 26

Parkinson's Disease

Question 27

Rationale behind neuroleptics:

Answer 27

reduce DA levels | are DA antagonists

Question 28

Rationale behind antidepressants:

Answer 28

increase NE and/or 5-HT levels

Question 29

Two classes of neuroleptics:

Answer 29

Typical and Atypical neuroleptics

Question 30

Typical neuroleptics target...

Answer 30

the nigrostriatal and mesolimbic pathway

Question 31

Atypical neuroleptics target...

Answer 31

the mesolimbic pathway

Question 32

Side effects of typical neuroleptics include:

Answer 32

Extrapyramidal Symptoms: involuntary tremors, movement disorders

Question 33

Haloperidol (Haldol) is in a class of _ called _

Answer 33

Antipsychotics, TYPICAL neuroleptics

Question 34

Risperidone (Risperdal) is in a class of _ called _

Answer 34

Antipsychotics, ATYPICAL neuroleptics

Question 35

Side effects of typical neuroleptics come from unintentional targeting of _ pathway

Answer 35

nigrostriatal

Question 36

Diazepam (Valium) is classified as an _ and _

Answer 36

Anxiolytic, Hypnotic

Question 37

Diazepam inhibits CNS activity by _

Answer 37

enhancing GABA effect

Question 38

Benzodiazepines are used short-term because...

Answer 38

the abuse potential is high

Question 39

Benzodiazepines are used as _, _, and _, but can also function as an _ .

Answer 39

anxiolytic; hypnotic; muscle relaxer; anti-seizure agent

Question 40

Buspirone (Buspar) is a _ that works as a __ agonist.

Answer 40

anxiolytic; 5-HT receptor

Question 41

Diazepam (Valium) is in a class of _ & _ called _

Answer 41

anxiolytics & hypnotics; benzodiazepines

Question 42

Diazepam (Valium) and Buspirone (Buspar) are both _.

Answer 42

anxiolytics

Question 43

Diazepam (Valium) is a _ whereas Buspirone (Buspar) is not.

Answer 43

hypnotic

Question 44

Fluoxetine (Prozac) and Amitryptyline (Elavil) are both _.

Answer 44

antidepressants

Question 45

Haloperidol (Haldol) and Risperidone (Risperdal) are both _.

Answer 45

antipsychotics

Question 46

Haloperidol (Haldol) is associated with _ whereas Risperidone (Risperdal) is not.

Answer 46

Extrapyramidal symptoms