super dick Flashcards
(240 cards)
1
Q
True/False: Agonists possess affinity only
A
FALSE- Antagonists possess affinity only
2
Q
True/False: The 1st pass effect applies to drugs administered orally
A
TRUE
3
Q
True/False: The uncharged form of a weak base with a pKa=8.2 would be most abundant at a pH=1.6
A
FALSE- A weak base will dissociate in an acidic solution and the charged form will dominate
4
Q
True/False: The charged form of a weak acid with a pKa=4.3 would be most abundant at a pH=2.8
A
FALSE- A weak acid will not dissociate in an acidic solution and the uncharged form will dominate
5
Q
True/False: If drug A is more potent than drug B, then drug B is more efficacious than drug A
A
FALSE
6
Q
True/False: Pareneteral administration of a drug is the most effect route of administration
A
FALSE
7
Q
True/False: Pharmocodynamics deals with the effects of a drug on the body
A
TRUE
8
Q
The liver plays a major role in drug excretion
A
TRUE
9
Q
Drugs administered IV have 1000% bioavailability
A
TRUE
10
Q
True/False: Tachycardia can result from the administration of metoprolol because it has β1 affinity
A
FALSE
11
Q
True/False: Tachycardia can result from the administration of bethanecol because it is a direct-acting muscarinic agonist
A
FALSE
12
Q
True/False: Tachycardia can result from the administration of neostigmine because it is a muscarinic antagonist
A
FALSE
13
Q
True/False: Tachycardia can result from the administration of phenylephrine because it increases SVR
A
FALSE
14
Q
True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will stimulate E secretion from the adrenal medulla
A
TRUE
15
Q
True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will cause diarrhea by directly stimulating β2 receptors
A
FALSE
16
Q
True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will decrease SVR by directly stimulating α1 receptors
A
FALSE
17
Q
True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will cause spastic skeletal muscle paralysis
A
FALSE
18
Q
True/False: Epinephrine is a positive chronotrope
A
TRUE
19
Q
True/False: Epinephrine decreases digestive system activity due to its β2 effect
A
TRUE
20
Q
True/False: Epinephrine is a positive inotrope
A
TRUE
21
Q
True/False: Epinephrine is a vasoconstrictor due to its α1 effect
A
TRUE
22
Q
True/False: Epinephrine is a vasodilator due to its β2 effect
A
TRUE
23
Q
True/False: Epinephrine is a bronchodilator due to its β2 effect
A
TRUE
24
Q
True/False: Atropine relaxes skeletal muscle because it is a cholinergic receptor antagonist
A
FALSE
25
True/False: Atropine is a positive chronotrope because it is an antimuscarinic drug
TRUE
26
True/False: Atropine decreases bronchial mucous secretion by blocking Nn receptors
FALSE
27
True/False: Atropine is a bronchodilator
TRUE
28
True/False: Labetalol causes reflex tachycardia
FALSE
29
True/False: Labetalol is a vasodilator
TRUE
30
True/False: Labetalol can cause orthostatic hypotension by blocking adrenergic receptors
TRUE
31
True/False: Labetalol lowers BP by reducing CO
TRUE
32
True/False: Metoprolol lowers BP by reducing SVR
FALSE
33
True/False: Metoprolol directly reduces CO
TRUE
34
True/False: Metoprolol targets the same receptors as dobutamine
TRUE
35
True/False: Metoprolol causes reflex bradycardia
FALSE
36
True/False: Phenylephrine causes reflex bradycardia because it reduces BP
FALSE
37
True/False: Phenylephrine targets a receptor targeted by NE
TRUE
38
True/False: Phenylephrine directly increases myocardial contractility
FALSE
39
True/False: Phenylephrine is an effective decongestant
TRUE
40
ACE Inhibitors AND/OR Cardioselective beta blockers block AII production
ACE INHIBITORS
41
ACE Inhibitors AND/OR Cardioselective beta blockers lower BP by reducing SVR
ACE INHIBITORS
42
ACE Inhibitors AND/OR Cardioselective beta blockers decrease LV afterload by reducing blood volume
NEITHER
43
ACE Inhibitors AND/OR Cardioselective beta blockers can successfully treat CHF
BOTH
44
ACE Inhibitors AND/OR Cardioselective beta blockers can cause hypokalemia
NEITHER
45
ACE Inhibitors AND/OR Cardioselective beta blockers decrease myocardial workload
ACE INHIBITORS
46
ARB's AND/OR CA++ Channel Blockers are vasodilators
BOTH
47
ARB's AND/OR CA++ Channel Blockers reduce SVR
BOTH
48
ARB's AND/OR CA++ Channel Blockers decrease AII production
NEITHER
49
ARB's AND/OR CA++ Channel Blockers can cause hypokalemia
NEITHER
50
ARB's AND/OR CA++ Channel Blockers are negative chronotropes
CA++ CHANNEL BLOCKERS
51
Dobutamine AND/OR Digoxin is useful in the treatment of systolic heart failure
BOTH
52
Dobutamine AND/OR Digoxin inhibits the Na/K pump
DIGOXIN
53
Dobutamine AND/OR Digoxin is a β1 agonist
DOBUTAMINE
54
Dobutamine AND/OR Digoxin is a positive inotrope
BOTH
55
HCTZ AND/OR Furosemide reduces preload by reducing SVR
NEITHER
56
HCTZ AND/OR Furosemide targets the DCT
HCTZ
57
HCTZ AND/OR Furosemide increases Na absorption in the renal tubules
NEITHER
58
HCTZ AND/OR Furosemide can cause hypokalemia
BOTH
59
True/False: A hypertensive patient would benefit from clonidine because it reduces CO
TRUE
60
True/False: A hypertensive patient would benefit from atenolol because it reduces stroke volume
TRUE
61
True/False: A hypertensive patient would benefit from Lisinopril because it reduces LV afterload
TRUE
62
True/False: A hypertensive patient would benefit from diltiazem because it is a negative inotrope
TRUE
63
True/False: A hypertensive patient would benefit from labetalol because it is a vasodilator
TRUE
64
True/False: Nitroglycerin reduces myocardial O2 demand
TRUE
65
True/False: Isosorbide dintrate reduces adterload by dilating veins
FALSE
66
True/False: Aspirin is indicated in patients at risk for DVTs
FALSE
67
True/False: Statins reduce hepatic cholesterol synthesis b inhibiting HMG CoA reductase
TRUE
68
True/False: Warfarin blocks the synthesis of vitamin K dependent clotting factors
TRUE
69
True/False: Heparin enhances ATIII activity
TRUE
70
True/False: Thrombolytics promote the conversion of plasminogen to plasmin
TRUE
71
True/False: A hypertensive patient would benefit from HCTZ because it is a positive inotrope
FALSE
72
True/False: Caffeine is a bronchodilator
TRUE
73
True/False: Ethanol is a myocardial depressant
TRUE
74
Cocaine AND/OR Nicotine is a CNS depressant
NEITHER
75
Cocaine AND/OR Nicotine can increase BP
BOTH
76
Cocaine AND/OR Nicotine has therapeutic benefit
BOTH
77
Cocaine AND/OR Nicotine is an alpha 2 agonist
NEITHER
78
Cocaine AND/OR Nicotine can increase heart rate
BOTH
79
Cocaine AND/OR Nicotine binds to receptors found in the autonomic nervous system
NICOTINE
80
Cocaine AND/OR Nicotine binds to receptors found in the somatic nervous system
NICOTINE
81
Albuterol AND/OR salmeterol is a rapid acting b2 agonist
ALBUTEROL
82
Albuterol AND/OR salmeterol is a bronchodilator
BOTH
83
Albuterol AND/OR salmeterol is a muscarinic receptor agonist
NEITHER
84
Albuterol AND/OR salmeterol is used as a "rescue" agent
ALBUTEROL
85
Albuterol AND/OR salmeterol reduces airway wall inflammation
NEITHER
86
Fluticasone AND/OR montelukast is a slow-acting bronchodilator
NEITHER
87
Fluticasone AND/OR montelukast is used as a "rescue" agent
NEITHER
88
Fluticasone AND/OR montelukast is a corticosteroid
FLUTICASONE
89
Fluticasone AND/OR montelukast is a leukotriene receptor antagonist
MONTELUKAST
90
Fluticasone AND/OR montelukast is an anti-inflammatory
BOTH
91
Insulin AND/OR sitagliptin can cause hypoglycemia
BOTH
92
Insulin AND/OR sitagliptin is a DPP-4 inhibitor
SITAGLIPTIN
93
Insulin AND/OR sitagliptin stimulates insulin secretion
SITAGLIPTIN
94
Insulin AND/OR sitagliptin is an insulin analogue
NEITHER
95
Insulin AND/OR sitagliptin is useful in the treatment of Type I diabetes
INSULIN
96
Exenatide AND/OR metformin stimulates insulin secretion
EXENATIDE
97
Exenatide AND/OR metformin can cause hypoglycemia
BOTH
98
Exenatide AND/OR metformin increases insulin sensitivity
METFORMIN
99
Exenatide AND/OR metformin is useful in the treatment of Type II diabetes
BOTH
100
True/False: Morphine causes respiratory depression
TRUE
101
True/False: Opiod analgesics are also effective antipyretics
FALSE
102
True/False: Acetaminophen is a non-opiod NSAID
FALSE
103
True/False: Aspirin's antiplatelet effects are cause by COX-1 inhibition
TRUE
104
Albuterol (Proventil) is in a class of _ called _
Bronchodilators, β2 agonists
105
Salmeterol (Advair) is in a class of _ called _
Bronchodilators, β2 agonists
106
Ipratropium (Atrovent) is in a class of _ called _
Bronchodilators, Anticholinergics
107
Tiotropium (Spiriva) is in a class of _ called _
Bronchodilators, Anticholinergics
108
Theophylline (Theo-24, Theolair, Uniphyl) is in a class of _ called _
Bronchodilators, Methylxanthines
109
Fluticasone (Advair, Flonase) is in a class of _ called _
Anti-Inflammatories, Corticosteroids
110
Phenolphthalein (X-Lax) is in a class of _ called _
Laxatives, Stimulants
111
Diphenoxylate (Lomotil) is in a class of _ called _
Anti-diarrheals, Opiods
112
Loperamide (Immodium) is in a class of _ called _
Anti-diarrheals, Opiods
113
Glipizide (Glucotrol) is in a class of _ called _
antidiabetics, Sulfonylureas
114
Exenatide (Byetta) is in a class of _ called _
antidiabetics, Incretin analogues
115
Sitagliptin phosphate (Januvia) is in a class of _ called _
antidiabetics, DPP-IV Inhibitors
116
Metformin is in a class of _ drugs called _
antidiabetics, biguanides
117
Diltiazem (Cardizem) is in a class of drugs called _
Ca++ Channel Blockers
118
Atenolol (Tenormin) is in a class of drugs called _
β1 Blockers
119
Nifedipine (Procardia) is in a class of drugs called _
Ca++ Channel Blockers
120
Captopril (Capoten) is in a class of drugs called _
Angiotensin-Converting-Enzyme Inhibitors
121
Losartan (Cozaar) is in a class of drugs called _
Angiotensin II Receptor Blockers
122
Lisinopril (Prinivil) is in a class of drugs called _
Angiotensin-Converting-Enzyme Inhibitors
123
Clonidine (Catapres) is in a class of drugs called _
Central Sympatholytics
124
Amlodipine (Norvasc) is in a class of drugs called _
Ca++ Channel Blockers
125
Metoprolol (Lopressor) is in a class of drugs called _
β1 Blockers
126
Hydralazine (Apresoline) is in a class of drugs called _
Direct Arterial Dilators
127
Verapamil (Calan) is in a class of drugs called _
Ca++ Channel Blockers
128
Hydrochlorothiazide (Esidrix) is in a class of drugs called _
DCT Diuretics
129
Prazosin (Minipress) is in a class of drugs called _
α1 Blockers
130
Nitroglycerin (Nitrolingual) is in a class of drugs called _
Nitrate- Arterial & Venous Dilators
131
Labetalol (Trandate) is in a class of drugs called _
α1, β1, β2 Blockers
132
Nitroprusside sodium (Nitropress) is in a class of drugs called _
Arterial & Venous Dilators
133
Aspirin (Ecotrin) is in a class of blood thinners called _
Antithrombics
134
Clopidogrel (Plavix) is in a class of blood thinners called _
Antithrombics
135
Abciximab (ReoPro) is in a class of blood thinners called _
Antithrombics
136
Heparin is in a class of blood thinners called _
Anticoagulants
137
Warfarin (Coumadin) is in a class of blood thinners called _
Anticoagulants
138
Dabigatron (Pradaxa) is in a class of blood thinners called _
Anticoagulants
139
Apixiban (Eliquis) is in a class of blood thinners called _
Anticoagulants
140
Streptokinase is in a class of blood thinners called _
Thrombolytics
141
Tissue plasminogen activator (t-PA) is in a class of blood thinners called _
Thrombolytics
142
Dobutamine (Dobutamine) is in a class of drugs called _
β1 Agonists
143
Digoxin (Digox) is in a class of drugs called _
Cardiac glycosides
144
Enoxaparin (Lovenox) is in a class of drugs called _
Anticoagulants
145
Furosemide (Lasix) is in a class of drugs called _
Loop Diuretics
146
Amiloride (Midamor) is in a class of drugs called _
K+ Sparing Diuretics
147
Triamterene (Dyrenium) is in a class of drugs called _
K+ Sparing Diuretics
148
Spironolactone (Aldactone) is in a class of drugs called _
K+ Sparing Diuretics, Aldosterone Antagonists
149
Mannitol (Osmitrol) is in a class of drugs called _
Osmotic Diuretics
150
Pravastatin Sodium (Pravachol) is in a class of drugs called _
Statins
151
Atorvastatin Calcium (Lipitor) is in a class of drugs called _
Statins
152
Simvastatin (Zocor) is in a class of drugs called _
Statins
153
Rosuvastatin Calcium (Crestor) is in a class of drugs called _
Statins
154
Isosorbide dinitrate (Dilatrate-SR) is in a class of drugs called _
Nitrate Venous Dilators
155
(D/(*/~))(nmab)(+/-): Neostigmine
Indirect (~reuptake) cholinomimetic
156
(D/(*/~))(nmab)(+/-): Nicotine
Direct nicotinic receptor agonist
157
(D/(*/~))(nmab)(+/-): Bethanechol
Direct muscarinic receptor agonist
158
(D/(*/~))(nmab)(+/-): Methamphetamine
Indirect (*release) sympathomimetic
159
(D/(*/~))(nmab)(+/-): MAOI
Indirect (~reuptake) sympathomimetic
160
(D/(*/~))(nmab)(+/-): TCA
Indirect (~reuptake) sympathomimetic
161
(D/(*/~))(nmab)(+/-): Cocaine
Indirect (~reuptake) sympathomimetic
162
(D/(*/~))(nmab)(+/-): Epinephrine
α1, α2, β1, β2 direct adrenergic receptor agonist
163
(D/(*/~))(nmab)(+/-): NE/Levophed
α1, α2, β1 direct adrenergic receptor agonist
164
(D/(*/~))(nmab)(+/-): Phenylephrine
α1 direct adrenergic receptor agonist
165
(D/(*/~))(nmab)(+/-): Clonidine
α2 adrenergic receptor agonist
166
(D/(*/~))(nmab)(+/-): Dobutamine
β1 adrenergic receptor agonist
167
(D/(*/~))(nmab)(+/-): Albuterol/Terbutaline
β2 adrenergic receptor agonist
168
(D/(*/~))(nmab)(+/-): "ganglionic blockers"
Nn cholinergic receptor antagonist
169
(D/(*/~))(nmab)(+/-): Atracurium
Nm cholinergic receptor antagonist
170
(D/(*/~))(nmab)(+/-): Vecuronium
Nm cholinergic receptor antagonist
171
(D/(*/~))(nmab)(+/-): Succinylcholine
Nm cholinergic antagonist
172
(D/(*/~))(nmab)(+/-): Atropine
Muscarinic receptor antagonist
173
(D/(*/~))(nmab)(+/-): Glycopyrrolate
Muscarinic receptor antagonist
174
(D/(*/~))(nmab)(+/-): Ipratropium
Muscarinic receptor antagonist
175
(D/(*/~))(nmab)(+/-): Tiotropium
Muscarinic receptor antagonist
176
(D/(*/~))(nmab)(+/-): Propanolol
Beta blocker
177
(D/(*/~))(nmab)(+/-): Prazosin
α1 blocker
178
(D/(*/~))(nmab)(+/-): Labetalol
α1, β1, β2 blocker
179
(D/(*/~))(nmab)(+/-): Metoprolol
β1 blocker
180
(D/(*/~))(nmab)(+/-): Atenolol
β1 blocker
181
Name me a non-selective beta blocker
Propanolol
182
Give me some weirdly pseudo opposite drugs (an agonist and an antagonist)
NE stimulates α1, α2, β1 Labetalol blocks α1, β1, β2
183
What receptor mediates reflexive tachycardia?
β1 receptors
184
Name me some β1 blockers
MetoprololAtenolol(Propanolol)(Labetalol)
185
Name me some α1 blockers
Prazosin(Labetalol)
186
Give me α1, α2, β1, β2 agonists in order
PhenylephrineClonidineDobutamineAlbuterol/Terbutaline
187
Give me our three cholinergic agonists
Neostigmine (~ cholinomimetic)Nicotine (D m cholinomimetic)Bethanechol (D m cholinomimetic)
188
Give me our three antinicotinics (m)
AtracuriumVecuroniumSuccinylcholine
189
Give me our four antimuscarinics
AtropineGlycopyrrolateIpratropiumTiotropium
190
What are beta blockers never
Beta blockers are never vasodilators
191
What is atracurium used for?
blocks nm junctionsflaccid paralysis
192
What is vecuronium used for?
blocks nm junctionsflaccid paralysis
193
What is succinylcholine used for?
blocks nm junctions(irreversible, short term) flaccid paralysis
194
What is atropine used for?
blocks M2 siteincreases HRtreat sinus bradycardia
195
What is glycopyrrolate used for?
blocks M3reduce glandular activityreduce bronchial secretions
196
What is ipratropium used for?
blocks M3relaxes s.m.treats COPD
197
What is tiotropium used for?
blocks M3relaxes s.m.treats COPD
198
What is propanolol used for?
blocks β1, β2slows HR, constricts s.m.treats hypertension
199
What is labetalol used for?
blocks α1, β1, β2vasodilation, slows HR, constricts s.m.treats emergency hypertension
200
What is prazosin used for?
blocks α1vasodilationreduces blood pressure
201
What is metoprolol used for?
blocks β1slows HRtreats congestive heart failure
202
What is atenolol used for?
blocks β1slows HRtreats congestive heart failure
203
What is neostigmine used for?
reduces ACh reuptakereverses paralyzing blockers
204
What is nicotine used for?
stimulates N receptorsenergy boost and P/SNS enhancement
205
What is bethanechol used for?
stimulates M3 cellstreats urinary problems
206
What is meth used for?
increases NE releasestimulant
207
What is cocaine used for?
reduce NE reuptakestimulant
208
What is epinephrine used for?
stimulates α1, α2, β1, β2vasoconstriction, reduces SNS, increases HR, relaxes s.m.
209
What is norepinephrine used for?
stimulates α1, α2, β1 vasoconstriction, reduces SNS, increases HR
210
What is levophed used for?
stimulates α1, α2, β1 vasoconstriction, reduces SNS, increases HR
211
What is phenylephrine used for?
stimulates α1vasoconstriction
212
What is clonidine used for?
stimulates α2reduces SNS
213
What is dobutamine used for?
stimulates β1increases HRtreats heart failure
214
What is albuterol used for?
stimulates β2relaxes s.m.tocolytic
215
What is terbutaline used for?
stimulates β2relaxes s.m.bronchodilator
216
Complete the equation: BP = ?
BP = CO x SVR
217
Complete the equation: CO = ?
CO = HR x SV
218
Complete the equation: SV = ?
Myocardial contractility x
219
When does baroreceptor reflex occur?
Change in BP
220
What group of drugs prevents the baroreceptor reflex?
Beta blockers
221
What two conditions can the baroreceptor reflex cause?
Reflexive tachycardiaReflexive bradycardia
222
Specifically what receptor mediates the baroreceptor reflex?
β1 receptors
223
Eight ways to treat hypertension!
DiureticsBeta blockersACE Inhibitors/ARBsCa++ channel blockersCentral sympatholyticsα1 blockersDirect arterial dilators
224
Name four classes of diuretics
Loop diuretics- Furosemide DCT diuretics- HCTZK+ sparing- Ameloride, Triamterene, SpironolactoneOsmotics- Mannitol
225
Name your drugs that affect angiotensin (at all)
CaptoprilLisinoprilLoSARtin
226
Name your Ca++ channel blockers
NifedipineAmlodipineDiltiazemVerapamil
227
Name some standalone drugs for hypertensive treatment (drugs who's class we know like one of)
Central sympatholytics- clonidineα1 blockers- prazosinDAD- hydralazine
228
Drugs to treat angina pectoris?
NitratesBeta blockersCa++ channel blockers
229
Name your nitrates
NitroglycerinIsosorbide dintrate
230
Drugs to treat hypertensive emergency
LabetalolNitroprusside Na
231
Drugs to treat systolic heart failure
DobutamineDigoxin
232
Generally how to treat systolic heart failure?
Improve contractilityReduce workload
233
Generally how to treat diastolic heart failure?
Increase filling timeReduce workload
234
How to reduce workload?
Reduce SNS activityReduce fluid retention
235
Drugs to reduce workload
DiureticsACE Inhibitors, ARBsBeta blockersNitroprusside Na
236
Drugs to increase filling time
Beta blockersCa ++ Channel blockersACE Inhibitors/ARBsDiuretics
237
Heart drugs that affect just preload?
Diuretics
238
Heart drugs that affect preload and afterload?
ACE Inhibitors, ARBsNitroprusside Na
239
Heart drugs that affect just afterload?
NONE HAHAHAHAHAHAHAHAHAHAHAH
240
Heart drugs that affect neither preload nor afterload?
Beta blockers
