super final awfully specific exam questions Flashcards

(103 cards)

1
Q

True/False: Agonists possess affinity only

A

FALSE- Antagonists possess affinity only

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2
Q

True/False: The 1st pass effect applies to drugs administered orally

A

TRUE

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3
Q

True/False: The uncharged form of a weak base with a pKa=8.2 would be most abundant at a pH=1.6

A

FALSE- A weak base will dissociate in an acidic solution and the charged form will dominate

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4
Q

True/False: The charged form of a weak acid with a pKa=4.3 would be most abundant at a pH=2.8

A

FALSE- A weak acid will not dissociate in an acidic solution and the uncharged form will dominate

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5
Q

True/False: If drug A is more potent than drug B, then drug B is more efficacious than drug A

A

FALSE

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6
Q

True/False: Pareneteral administration of a drug is the most effect route of administration

A

FALSE

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7
Q

True/False: Pharmocodynamics deals with the effects of a drug on the body

A

TRUE

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8
Q

The liver plays a major role in drug excretion

A

TRUE

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9
Q

Drugs administered IV have 1000% bioavailability

A

TRUE

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10
Q

True/False: Tachycardia can result from the administration of metoprolol because it has β1 affinity

A

FALSE

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11
Q

True/False: Tachycardia can result from the administration of bethanecol because it is a direct-acting muscarinic agonist

A

FALSE

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12
Q

True/False: Tachycardia can result from the administration of neostigmine because it is a muscarinic antagonist

A

FALSE

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13
Q

True/False: Tachycardia can result from the administration of phenylephrine because it increases SVR

A

FALSE

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14
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will stimulate E secretion from the adrenal medulla

A

TRUE

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15
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will cause diarrhea by directly stimulating β2 receptors

A

FALSE

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16
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will decrease SVR by directly stimulating α1 receptors

A

FALSE

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17
Q

True/False: A patient is administered a drug that stimulates nicotinic neuronal receptors. The drug will cause spastic skeletal muscle paralysis

A

FALSE

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18
Q

True/False: Epinephrine is a positive chronotrope

A

TRUE

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19
Q

True/False: Epinephrine decreases digestive system activity due to its β2 effect

A

TRUE

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20
Q

True/False: Epinephrine is a positive inotrope

A

TRUE

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21
Q

True/False: Epinephrine is a vasoconstrictor due to its α1 effect

A

TRUE

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22
Q

True/False: Epinephrine is a vasodilator due to its β2 effect

A

TRUE

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23
Q

True/False: Epinephrine is a bronchodilator due to its β2 effect

A

TRUE

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24
Q

True/False: Atropine relaxes skeletal muscle because it is a cholinergic receptor antagonist

A

FALSE

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25
True/False: Atropine is a positive chronotrope because it is an antimuscarinic drug
TRUE
26
True/False: Atropine decreases bronchial mucous secretion by blocking Nn receptors
FALSE
27
True/False: Atropine is a bronchodilator
TRUE
28
True/False: Labetalol causes reflex tachycardia
FALSE
29
True/False: Labetalol is a vasodilator
TRUE
30
True/False: Labetalol can cause orthostatic hypotension by blocking adrenergic receptors
TRUE
31
True/False: Labetalol lowers BP by reducing CO
TRUE
32
True/False: Metoprolol lowers BP by reducing SVR
FALSE
33
True/False: Metoprolol directly reduces CO
TRUE
34
True/False: Metoprolol targets the same receptors as dobutamine
TRUE
35
True/False: Metoprolol causes reflex bradycardia
FALSE
36
True/False: Phenylephrine causes reflex bradycardia because it reduces BP
FALSE
37
True/False: Phenylephrine targets a receptor targeted by NE
TRUE
38
True/False: Phenylephrine directly increases myocardial contractility
FALSE
39
True/False: Phenylephrine is an effective decongestant
TRUE
40
ACE Inhibitors AND/OR Cardioselective beta blockers block AII production
ACE INHIBITORS
41
ACE Inhibitors AND/OR Cardioselective beta blockers lower BP by reducing SVR
ACE INHIBITORS
42
ACE Inhibitors AND/OR Cardioselective beta blockers decrease LV afterload by reducing blood volume
NEITHER
43
ACE Inhibitors AND/OR Cardioselective beta blockers can successfully treat CHF
BOTH
44
ACE Inhibitors AND/OR Cardioselective beta blockers can cause hypokalemia
NEITHER
45
ACE Inhibitors AND/OR Cardioselective beta blockers decrease myocardial workload
ACE INHIBITORS
46
ARB's AND/OR CA++ Channel Blockers are vasodilators
BOTH
47
ARB's AND/OR CA++ Channel Blockers reduce SVR
BOTH
48
ARB's AND/OR CA++ Channel Blockers decrease AII production
NEITHER
49
ARB's AND/OR CA++ Channel Blockers can cause hypokalemia
NEITHER
50
ARB's AND/OR CA++ Channel Blockers are negative chronotropes
CA++ CHANNEL BLOCKERS
51
Dobutamine AND/OR Digoxin is useful in the treatment of systolic heart failure
BOTH
52
Dobutamine AND/OR Digoxin inhibits the Na/K pump
DIGOXIN
53
Dobutamine AND/OR Digoxin is a β1 agonist
DOBUTAMINE
54
Dobutamine AND/OR Digoxin is a positive inotrope
BOTH
55
HCTZ AND/OR Furosemide reduces preload by reducing SVR
NEITHER
56
HCTZ AND/OR Furosemide targets the DCT
HCTZ
57
HCTZ AND/OR Furosemide increases Na absorption in the renal tubules
NEITHER
58
HCTZ AND/OR Furosemide can cause hypokalemia
BOTH
59
True/False: A hypertensive patient would benefit from clonidine because it reduces CO
TRUE
60
True/False: A hypertensive patient would benefit from atenolol because it reduces stroke volume
TRUE
61
True/False: A hypertensive patient would benefit from Lisinopril because it reduces LV afterload
TRUE
62
True/False: A hypertensive patient would benefit from diltiazem because it is a negative inotrope
TRUE
63
True/False: A hypertensive patient would benefit from labetalol because it is a vasodilator
TRUE
64
True/False: Nitroglycerin reduces myocardial O2 demand
TRUE
65
True/False: Isosorbide dintrate reduces adterload by dilating veins
FALSE
66
True/False: Aspirin is indicated in patients at risk for DVTs
FALSE
67
True/False: Statins reduce hepatic cholesterol synthesis b inhibiting HMG CoA reductase
TRUE
68
True/False: Warfarin blocks the synthesis of vitamin K dependent clotting factors
TRUE
69
True/False: Heparin enhances ATIII activity
TRUE
70
True/False: Thrombolytics promote the conversion of plasminogen to plasmin
TRUE
71
True/False: A hypertensive patient would benefit from HCTZ because it is a positive inotrope
FALSE
72
True/False: Caffeine is a bronchodilator
TRUE
73
True/False: Ethanol is a myocardial depressant
TRUE
74
Cocaine AND/OR Nicotine is a CNS depressant
NEITHER
75
Cocaine AND/OR Nicotine can increase BP
BOTH
76
Cocaine AND/OR Nicotine has therapeutic benefit
BOTH
77
Cocaine AND/OR Nicotine is an alpha 2 agonist
NEITHER
78
Cocaine AND/OR Nicotine can increase heart rate
BOTH
79
Cocaine AND/OR Nicotine binds to receptors found in the autonomic nervous system
NICOTINE
80
Cocaine AND/OR Nicotine binds to receptors found in the somatic nervous system
NICOTINE
81
Albuterol AND/OR salmeterol is a rapid acting b2 agonist
ALBUTEROL
82
Albuterol AND/OR salmeterol is a bronchodilator
BOTH
83
Albuterol AND/OR salmeterol is a muscarinic receptor agonist
NEITHER
84
Albuterol AND/OR salmeterol is used as a "rescue" agent
ALBUTEROL
85
Albuterol AND/OR salmeterol reduces airway wall inflammation
NEITHER
86
Fluticasone AND/OR montelukast is a slow-acting bronchodilator
NEITHER
87
Fluticasone AND/OR montelukast is used as a "rescue" agent
NEITHER
88
Fluticasone AND/OR montelukast is a corticosteroid
FLUTICASONE
89
Fluticasone AND/OR montelukast is a leukotriene receptor antagonist
MONTELUKAST
90
Fluticasone AND/OR montelukast is an anti-inflammatory
BOTH
91
Insulin AND/OR sitagliptin can cause hypoglycemia
BOTH
92
Insulin AND/OR sitagliptin is a DPP-4 inhibitor
SITAGLIPTIN
93
Insulin AND/OR sitagliptin stimulates insulin secretion
SITAGLIPTIN
94
Insulin AND/OR sitagliptin is an insulin analogue
NEITHER
95
Insulin AND/OR sitagliptin is useful in the treatment of Type I diabetes
INSULIN
96
Exenatide AND/OR metformin stimulates insulin secretion
EXENATIDE
97
Exenatide AND/OR metformin can cause hypoglycemia
BOTH
98
Exenatide AND/OR metformin increases insulin sensitivity
METFORMIN
99
Exenatide AND/OR metformin is useful in the treatment of Type II diabetes
BOTH
100
True/False: Morphine causes respiratory depression
TRUE
101
True/False: Opiod analgesics are also effective antipyretics
FALSE
102
True/False: Acetaminophen is a non-opiod NSAID
FALSE
103
True/False: Aspirin's antiplatelet effects are cause by COX-1 inhibition
TRUE