Anytime (perman done) (10.8) Flashcards

1
Q

to know which reactant in heme synthesis is able to absorb light…what do you have to know

A

porphyrin absorbs light

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2
Q

LCAT converts nascent HDL to mature HDL via what mec

A

esterify cholesterol

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3
Q

ETF function

A

needed in first step in beta oxidation

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4
Q

what marks the transition from retroperitoneal duodenum to intraperitoneal jejunum

A

suspensory ligament of duodenum

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5
Q

what ligament attaches the left colic flexure to the diaphragm

A

phrenicocolic ligament

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6
Q

circular folds

  • what are they
  • where
A

invaginations of mucosal lining in DD

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7
Q

what is a barium swallow

A

patient swallows barium

so that you can visualize the esophagus in a radiograph

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8
Q

esophageal hiatus is found in what organ

A

diaphragm

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9
Q

diverticula can (verb) arteries, leading to hemorrhage

A

erode

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10
Q

what diseases are linked to Xanthoma

A
  • chylomicronemia

- type 1 glycogen storage disease (also leads to fatty buildup on liver)

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11
Q

CETP function

A

transfers VLDL TAG to HDL

transfers HDL cholesterol ester to VLDL

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12
Q

which apo mediates chylomicron remnant uptake by the liver

which Apo is linked to aterosclerosis

A

liver-Apo E

ath-Apo A

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13
Q

familial hyper cholestero lemia is caused by

A

LDL receptor mutation

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14
Q

total cholesterol eq

A

VLDL + LDL + HDL

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15
Q

lab values for

CM 
VLDL 
IDL - skip  
LDL 
HDL
A
CM -TG 
VLDL - TG 
IDL 
LDL - total cholesterol (indirectly measured)  
HDL - directly measured
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16
Q

LDL clearance problem is due to what things

dyslipidemia is caused by what things

A

LDL receptor defect
Apo B 100 problem

dys 
1 mutation in lipase 
2 mut in Apo B 100 
3 mut in LDL R 
4 mut in Apo C 2
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17
Q

% values for what defines dyslipidemia

A

cholesterol, TG, LDL are over 90%

HDL is below 10%

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18
Q

why does HDL have an anti atherogenic effect

A

excess cholesterol is dumped onto HDL

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19
Q

tongue is derived from what kind of derm

A

pharyngeal endoderm

20
Q

periodontal ligament attaches what to what

A

tooth to bone

21
Q

dentin is from what derm

A

neural crest

22
Q

enamel is from what derm

A

ectoderm

23
Q

papilla is from what derm

A

neural crest

read: papilla comprises pulp

24
Q

which cells have tomes fibers

tomes processes

A

fibers - odontoblast

pro - ameloblast

25
Q

the terms mucous and serous are classifying what

A

acini glandular cell

in salivary gland

26
Q

in liver, glucose transport is controlled by (insulin/glucose)

how about in muscle

A

liver - glucose (LG)

muscle - insulin

27
Q

PLP, biotin, THF, SAM, THB are cofactors in AA (anabolism/cata)

A

catabolism

28
Q

centroacinar cell is found in what organ

A

pancreas

29
Q

insulin vs. glucagon and ??

A

epinephrine

30
Q

congenital lactic acidosis is due to

A

1 already know about the genetic pathway (mother mito gene etc)

2 def in pyruvate dehydrogenase (norm: py -> ACA)
cannot use pyruvate so lactate compensates

31
Q

what causes sudden infant death syndrome

what causes severe combined immunodef disease

A

SIDS - infant - MCAD

SCID - immunodef - ADA

32
Q

which disease is always part of the newborn screen

A

PKU

33
Q

which of the proteins mentioned in Winkler’s lecture has the shortest half life?

longest?

A

short - retinol binding protein

longest - albumin

34
Q

folds in SI are called what

A

plicae

35
Q

is spleen considered part of the foregut

A

NO

36
Q

fuels of hepatic GNG

A

lactate (glucose)
alanine (AA)
glycerol (fat)

37
Q

there’s only one vein in the adrenal gland (vs three arteries)

name the vein

A

suprarenal vein

38
Q

what ligaments form the openings for the psoas major muscle

how about for quadratus lumborum muscle?

A

psoas - medial arcuate ligament

q - lateral AL

39
Q

surgeons can repair an aneurysm - how

detailed

A

1 open the aneurysm, insert a graft, and sew back the wall of ab aorta

2 catheter

40
Q

median um fold/ligament is formed by what

A

urachus

41
Q

decreased muscle mass indicator

A

low creatine

in urine

42
Q

LPL def symptom

A

elevated TG

43
Q

Pompe disease mec and symptom

A

glycogen degraded in lysosomes via acid maltase/lysosomal glucosidase

def in enzyme (acid maltase)

neonatal cardiomyopathy

44
Q

mec of homo cystinuria

A

def in cystathionine synthase

45
Q

most common heme synthesis defect

A

P cutanea tarda

PCT

46
Q

read: def in ferrochelatase = disease is called erythropoetic porphyria

A

-