Flashcards in ART Therapy (lecture) Deck (20):
What is the expected increase in CD4 counts of people on effective ART therapy?
2x baseline every 3 - 6 months
What 4 conditions may indicate deferral of ART?
Barriers to adherence
Co morbidities complicate ART
What are the thee strategies of ART polyRx?
2 x NRTI + PI
2 x NRTI + NNRTI
2 x NRTI + integrase inhibitor
Lamivudine, Abacavir, Tenofovir, and Emtricitabine are all examples of what class of drugs?
Which NRTI has the highest incidence of hypersensitivity?
What NRTI is given as a prophylactic for vertical transmission?
Note: This is a nucleoTIDE (not side)
What is the most commonly prescribed NNRTI?
What is an absolute contraindication of Efavirenz?
Pregnancy, it is teratogenic
What is the suffix common to all protease inhibitors?
What metabolic abnormalities are a common side effect of protease inhibitors?
What protease inhibitor is synergistic with other PIs?
What is the most common side effect of Indinavir?
Kidney stones (made of the drug itself)
What dietary restriction is indicated in Atazanavir use?
Milk may inhibit absorption
What is the first line protease inhibitor?
What is the MoA of Enfuvirtide?
Fusion inhibitor (enFUvirtide prevents inFUsion) by blocking gp41
What is the MoA of Maraviroc?
Inhibits binding of HIV to CCR5 (maraviROC blocks binding)
What is the common suffix of integrase inhibitors?
What are the ARTs, from least to most commonly used?
HaHa. Just kidding. This changes too much for it to be tested. If you want to know, look at the lecture.
What is the immediate treatment given to neonates from an HIV + mother?