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Flashcards in HIV Comorbidity (lecture) Deck (14):
1

What single ART Rx has the lowest association of hyperlipidemia? What is its classification and mechanism?

Tenofovir is a nucleoTIDE analog that results in reverse transcriptase chain termination

2

What is the first line treatment of isolated high LDL?

Statins

3

What is the first line treatment of isolated high TG?

Fibrate (ex. gemfibrozil, fenofibrate)

4

Patient with 4 g/day proteinuria, CD4 count of 150, renal hypertrophy, hypertension. He has shown a significant increase in CD 4 counts over the past 3 months since starting ART. What classification of medication should be added? What is expected on histology of his kidneys?

- CKD - ACE inhibitors (-pril) are first line treatment
- IgA deposits in the mesangium and glomerular capillary wall

5

What is the typical CD 4 count that leaves a patient susceptible to Mycobacterium avid-intracellulare?

less than 50

6

What is the first line Rx treatment in osteoporosis in HIV patients?

Bisphosphonates (-dronates)

7

What is the single most important risk factor of CVD in HIV patients?

Smoking

8

Patient with HIV and successful ART therapy arrives with a random glucose of 220 and HbA1c of 8.0. What are the two most important treatments for controlling this patient's DM?

Healthy life style (exercise and diet)
Metformin

9

What is the first line treatment of isolated high LDL?

Statins

10

What is the first line treatment of isolated high TG?

Fibrate (ex. gemfibrozil, fenofibrate)

11

Patient with 4 g/day proteinuria, CD4 count of 150, renal hypertrophy, hypertension. He has shown a significant increase in CD 4 counts over the past 3 months since starting ART. What classification of medication should be added? What is expected on histology of his kidneys?

- CKD - ACE inhibitors (-pril) are first line treatment
- IgA deposits in the mesangium and glomerular capillary wall

12

What is the first line Rx treatment in osteoporosis in HIV patients?

Bisphosphonates (-dronates)

13

What is the single most important risk factor of CVD in HIV patients?

Smoking

14

Patient with HIV and successful ART therapy arrives with a random glucose of 220 and HbA1c of 8.0. What are the two most important treatments for controlling this patient's DM?

Healthy life style (exercise and diet)
Metformin