Flashcards in Transplant Intro (lecture) Deck (12):
1
What is the anti-CD52 antibody covered in class?
Alemtuzumab - CD52 is believed to be part of lymphocyte activation
2
What are the two anti-IL2 receptor antibodies covered in class?
Basiliximab
Dacliximab
3
What are the two clacineurins covered in class?
Cylcosporine
Tacrolimus
4
What is the MoA of Azathioprine and Mycophenolate mofetil?
Inhibit DNA synth and preferentially target immune system cells
5
What are the two TOR (target of rapamycin) inhibitors?
Sirolimus
Everolimus
6
What two drugs target T-cell costimulation?
Belatacept
Abatacept
think of the T in both of them
7
Do you treat chronic rejection?
NO
8
Do you treat acute rejection?
Yes
9
What is the key cytokine in rejection?
IL-2
10
What is the cause of pneumonia in immunosuppressed patients on board questions?
CMV
11
What is the key cross matching?
MHC
12