Flashcards in Atypical pneumonia Deck (9):
Symptoms of atypical pneumonia
Non-productive cough, fever, maculopapular rash, bilateral crackles
Chest Xray result for atypical pneumonia
Bilateral fluffy infiltrates. Less “solid” and distinct. More in bronchi and bronchioles
Result of sputum for atypical pneumonia
Neutrophils but no organisms
Most likely causes of atypical pneumonia?
Mycoplasma pneumonia (Xray looks worse than patient)
Mycoplasma pneumoniae description
Small, no cell wall (no gram stain!), Virulence factors: has sterols like human cells (evades), P1 (binds epithelial cells), H2O2.
Mycoplasma pneumoniae pathogenesis
From droplets. Actually line up on bronchi and bronchioles, but not alveoli. H2O2 damages cilia and they die and slough off. Some ABs cross react and cause hemolysis or RBC agglutination at cold Temp
Extra-pulmonary symptoms of M pneumoniae
Rash, Cardiac abnormalities, Aseptic meningitis or encephalitis, Polyarthralgias
How to confirm Mycoplasm?
Hard, takes time. PCR, culture, or serology - usually a few weeks. Acid fast stain? No, only for TB