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Flashcards in Autoantibodies Deck (22):
1

Anti-Ach

Myasthenia gravis

2

Anti-basement membrane

Goodpasteur's syndrome

3

Anti-cardiolipin, lupus anticoagulant

SLE; antiphospholipid syndrome

4

Anticentromere

Limited scleroderma (CREST syndrome)

5

Anti-desmoglein

Pemphigus vulgaris

6

Anti-dsDNA, anti-Smith

SLE

7

Anti-glutamate decarboxylase

T1DM

8

Anti-hemidesmosome

Bullous pemphigus

9

Antihistone

Drug-induced lupus

10

Anti-Jo-1, anti-SRP, anti-Mi-2

Polymyositis, dermatomyositis

11

Antimicrosomal, antithyroglobulin

Hashimoto thyroiditis

12

Antimitochondrial

Primary biliary cirrhosis

13

Antinuclear antibodies

SLE (non-specific)

14

Anti-Scl-70 (anti-DNA topoisomerase I)

Scleroderma (diffuse)

15

Anti-smooth muscle

Autoimmune hepatitis

16

Anti-SSA, anti-SSB (anti-Ro, anti-La)

Sjogren syndrome

17

Anti-TSH receptor

Grave's disease

18

Anti-U1 RNP (ribonucleoprotein)

Mixed connective tissue disease

19

c-ANCA (PR3-ANCA)

Granulomatosis with polyangiitis (Wegener)

20

IgA antiendomysial, IgA anti-tissue transglutaminase

Celiac disease

21

p-ANCA

Microscopic polyangiitis, Churg-Strauss syndrome

22

Theumatoid factor (antibody, mostly commonly IgM, specific to IgG Fc region), anti-CCP

Rheumatoid arthritis