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Flashcards in Autoantibodies Deck (25):
1

Anti-ACh receptor

Myasthenia gravis

2

Anti-basement membrane

Goodpasture syndrome

3

Anticardiolipin, lupus anticoagulant

- SLE
- Antiphospholipid syndrome

4

Anticentromere

Limited scleroderma (CREST syndrome)

5

Anti-desmoglein (anti-desmosome)

Pemphigus vulgaris

6

Anti-dsDNA, anti-Smith

SLE

7

Anti-glutamic acid decarboxylase (GAD-65)

Type I DM

8

Antihemidesmosome

Bullous pemphigoid

9

Anti-histone

Drug-induced lupus

10

Anti-Jo-1, anti-SRP, anti-Mi-2

- Polymyositis
- Dermatomyositis

11

Antimicrosomal, antithyroglobulin

Hashimoto thryoiditis

12

Antimitochondrial

Primary biliary cirrhosis

13

Antinuclear (ANA)

- SLE
- Nonspecific

14

Antiparietal cell

Pernicious anemia

15

Antiphospholipase A2 receptor

Primary membranous nephropathy

16

Anti-Scl-70 (anti-DNA topoisomerase I)

Scleroderma (diffuse)

17

Anti-smooth muscle

Autoimmune hepatitis type 1

18

Anti-SSA, anti-SSB (anti-Ro, anti-La)

Sjogren syndrome

19

Anti-TSH receptor

Graves disease

20

Anti-U1 RNP (ribonucleoprotein)

Mixed connective tissue disease

21

Voltage-gated calcium channel antibodies

Lambert-Eaton syndrome

22

IgA anti-endomysial, IgA anti-tissue transglutaminase

Celiac disease

23

MPO-ANCA/p-ANCA

- Microscopic polyangiitis
- Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)

24

PR3-ANCA/c-ANCA

Granulomatosis with polyangiitis (Wegener)

25

Rheumatoid actor (IgM that targets IgG Fc region), anti-CCP (more specific)

Rheumatoid arthritis