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Flashcards in Common diseases of HIV-positive adults Deck (23):
1

CD4+ cell count 500

- Candida albicans (oral thrush)
- EBV (oral hairy leukoplakia)
- Bartonella henselae (bacillary angiomatosis)
- HHV-8 (Kaposi sarcoma)
- Cryptosporidium spp. (chronic, watery diarrhea)
- HPV (squamous cell carcinoma, common of anus or cervix)

2

CD4+ cell count 200

- HIV (dementia)
- JC virus reactivation (progressive multifocal leukoencephalopathy)
- Pneumocystis jirovecci (pnemocystis pneumonia)

3

CD4+ cell count 100

- Aspergillus fumigatus (hemoptysis, pleuritic pain)
- Cryptococcus neoformans (meningitis)
- Candida albicans (esophagitis)
- CMV (retinitis, esophagitis, colitis, pneumonitis, encephalitis)
- EBV (B-cell lymphoma - non-Hodgkin lymphoma, CNS lymphoma)
- Histoplasma capsulatum (fever, weight loss, fatigue, cough, dyspnea, nausea, vomitting, diarrhea
- Mycobacterium avium-intracellulare, MAC (nonspecific systemic symptoms - fever, night sweas, weight loss; lymphadenitis)
- Toxoplasma gondii (brain abscesses

4

Scrapable white plaque, pseudohyphae on microscopy

- Oral thrush by Candida albicans
- CD4+ 500

5

Unscrapable white plaque on lateral tongue

- Oral hairy leukoplakia by EBV
- CD4+ 500

6

Biopsy with neutrophilic inflammation

- Bacillary angiomatosis by Bartonella henselae
- CD4+ 500

7

Biopsy with lymphocytic inflammation

- Kaposi sarcoma by HHV-8
- CD4+ 500

8

Acid-fast oocysts in stool

- Chronic, watery diarrhea by Cryptosporidium spp.
- CD4+ 500

9

Squamous cell carcinoma (commonly of anus or cervix)

- HPV
- CD4+ 500

10

Dementia

- HIV
- CD4+ 200

11

Nonenhancing areas of demyelination on MRI

- Progressive multifocal leukoencephalopathy by JC virus
- CD4+ 200

12

"Ground-glass" opacities on CXR

- Pneumocystis pneumonia
- CD4+ 200

13

Cavitation or infiltrates on chest imaging

- Hemoptysis, pleuritc pain by Aspergillus fumigatus
- CD4+ 100

14

Encapsulated yeast on India ink stain or capsular antigen positive

- Meningitis by Cryptococcus neoformans
- CD4+ 100

15

White plaques on endoscopy; yeast and pseudohyphae on biopsy

- Esophagitis by Candida albicans
- CD4+ 100

16

Linear ulcers on endoscopy, cotton-wool spots on fundoscopy; biopsy reveals cells with intranuclear (owl-eye) inclusion bodies

- Retinitis, esophagitis, colitis, pneumonitits, encephalitis by CMV
- CD4+ 100

17

CNS lymphoma - ring enhancing, may be solitary

- B-cell lymphoma (non-Hodgkin lymphoma, CNS lymphoma) by EBV
- CD4+ 100

18

Oval yeast cells within macrophages

- Fever, weight, loss, fatigue, cough, dyspnea, nausea, vomitting, diarrhea by Histoplasma capsulatum

19

Nonspecific systemic symptoms (fever, night sweats, weight loss) or focal lymphadenitits

- Mycobacterium avium-intracellulare, MAC
- CD4+

20

Multiple ring-enhancing lesions on MRI

- Brain abscesses by Toxoplasma gondii
- CD4+

21

Prophylaxis CD4+ 200

- TMP-SMX
- Pneumocystis pneumonia

22

Prophylaxis CD4+ 100

- TMP-SMX
- Pneumocystis pneumonia and Toxoplasmosis

23

Prophylaxis CD4+ 50

- Azithromycin or clarithromycin
- Mycobacterium avium complex