Cell surface proteins Flashcards
1
Q
Present on all nucleated cells
A
- MHC I
- Remember not RBCs! (no nucleus!)
2
Q
T cells
A
- TCR (binds antigen-MHC complex)
- CD3 (associated with TCR for signal transduction)
- CD28 (binds B7 on APC)
- CCR5/CXCR4 (co-receptors for HIV)
3
Q
Helper T cells
A
- CD4
- CD40L
- TCR (binds antigen-MHC complex)
- CD3 (associated with TCR for signal transduction)
- CD28 (binds B7 on APC)
- CCR5/CXCR4 (co-receptors for HIV)
4
Q
Cytotoxic T cells
A
- CD8
- CXCR4/CCR5
- TCR (binds antigen-MHC complex)
- CD3 (associated with TCR for signal transduction)
- CD28 (binds B7 on APC)
- CCR5/CXCR4 (co-receptors for HIV)
5
Q
Regulatory T cells
A
- CD4
- CD25
- FOXP3
- TCR (binds antigen-MHC complex)
- CD3 (associated with TCR for signal transduction)
- CD28 (binds B7 on APC)
- CCR5/CXCR4 (co-receptors for HIV)
6
Q
B cells
A
- Ig (binds antigen)
- CD19
- CD20
- CD21 (EBV receptor)
- CD40
- MHC II
- B7
7
Q
Macrophages
A
- CD14 (receptor for PAMPs like LPS)
- CD40
- CCR5
- MHC II
- B7
- Fc and C3b receptors (enhanced phagocytosis)
8
Q
NK cells
A
- CD16 (binds Fc region of IgG)
- CD56 (unique marker for NK)
9
Q
Hematopoietic stem cells
A
CD34
