autonomics Flashcards
(81 cards)
a1 receptors (1 feature)
230 increase in intestinal and bladder spincter muscle contraction
a2 receptors
230 decreases lipoylisis, increase platelet aggregation, , decrease aqueous humor production
b1 receptor
increase lipolysis 230
b2 receptor
involved in hypokalemia, increase lipoylsis, 230
b3 receptor
increase lipolysis, increase thermogenesis in skeletal muscle, increase in bladder relaxation 230
m1 receptors
stimulates cognitive function, stimulates enteric nervous system
m2 receptors
230
m3 receptors
excorine glad secretions, (lacrimal, sweat, salivary, gastric acid), gut peristalsis, increase in insulin
d1 receptor
230
d1 receptor
230
h1 receptor
nasal and bronchial mucous production, vascular permeability and vasdoilation, contraction of bronchioles, pruitism pain
h2
230
amphetamine mech
releases stored catecholamines and inhibits reuptake
ephedrine mech
releases stored catecholamines
cocaine mech
reuptake inhibitor
TCA
reuptake inhibitor
how does a1 cause contraction in vascular smooth muscle?
through ip3 and increased Ca -> ca-calmodulin
how does b2 cause relaxation in vascular smooth muscle?
through increase camp-> pka -> phosphorylation of MLCK
how is nitric oxide formed and how does it cause relaxation?
formed by m3 on endothelium -> gq -> ca -> activated nitric oxide synthase -> increase NO -> guanlate cyclase -> increase cgmp -> phosphorylated mlcp
bathanechol
232
carbachol
232
methacholine
232
pilocarpine
232
galantamine
232
