micro pharm Flashcards
(302 cards)
1
Q
penicillin G route of administration?
A
183
2
Q
Pevcillin V route of administration?
A
183
3
Q
pencillin analg of?
A
183
4
Q
pencillin mechanism
A
183
5
Q
pencillin prevents?
A
183
6
Q
pencillin use?
A
183
7
Q
pencillin bactericidal for who?
A
183
8
Q
pencillin sensitive too?
A
183
9
Q
pencillin adverse effects
A
183
10
Q
pencillin resistance
A
183
11
Q
pencillinase sensitive penicillins names
A
184
12
Q
pencillinase sensitive penicillins combine with?
A
184
13
Q
amoxicillin better than apmpicillin how?
A
184
14
Q
pencillinase sensitive penicillins use
A
184
15
Q
pencillinase sensitive penicillins effects
A
184
16
Q
pencillinase sensitive penicillins resistance
A
184
17
Q
why is MRSA resistant to staph penicillins?
A
because altered binding proteins
18
Q
pencillinase sensitive penicillins resistance
A
184
19
Q
penicillinase resistant penicilins names
A
184
20
Q
penicillinase resistant penicilins mech
A
184
21
Q
penicillinase resistant penicilins use
A
184
22
Q
penicillinase resistant penicilins adverse
A
184
23
Q
antipseudomonal penicillins names
A
184
24
Q
antipseudomonal penicillins mech
A
184
25
antipseudomonal penicillins use
184
26
antipseudomonal penicillins adverse effects
184
27
antibiotics with anaerobic activity
clindamycin, metronidazole, augmentin, ticaercillin-clavulatante, pipericillin-tazobactam, carbepenems, moxifloxican, tigecycline
28
antipseudomonal penicillins adverse effects
184
29
piperacillin-tazobactam good for?
184
30
name the b lactamse inhibitors
184
31
cephalosporins mech
185
32
cephalosporins orgnisms not covered
185
33
cephalosporins 1st gen
185
34
cephalosporins 2nd gen
185
35
cephalosporins 3rd
185
36
cephalosporins 4th
185
37
cephalosporins 5th
185
38
cephalosporins 5th
185
39
uworld describes anaphlaxis, what were they taking, DOC to treat?
ceftrixaone (b lactam allergic)
epinephrine, then later steroid and antihistamines
40
ceftraxone works agaisnt?
h influ
kleb pneumonia
neisseria
serratia
41
what carbapenem does not work agaisnt pseudomonas?
ertapenem
42
carbapenem mech
186
43
carbapenem use
186
44
carbapenem adverse
186
45
carbapenem doc for
186
46
carbapenem doc for
186
47
monobactam names
186
48
monobactam mech
186
49
monobactam benefit
186
50
monobactam actions agaisnt (important)
186
51
monobactam use
186
52
monobactam adverse affects
186
53
vancomycin action
186
54
vancomycin bactericidial vs bacertiostatic
186
55
vancomycin not susceptible to?
186
56
vancomycin 1st line agaisnt?
186
57
vancomycin use
186
58
vancomycin effects
186
59
vancomycin mechanism of resistance
186
60
bactericidal protein synthesis inhibitor
aminoglycoside
61
bactericidal protein synthesis inhibitor etc
aminoglycoside, the rest are static except linezolid which is variable
62
aminioglycosides names
188
63
aminoglycosides imortant coverage
188
64
aminioglycoside mech
187
65
aminioglycoside clinical use
188
66
aminioglycoside clinical use
187
67
aminioglycoside adverse effect
187
68
aminioglycoside resistance
187
69
tetracyclines names
tetracyclins, doxycycline, minocycline
70
tetracycline with improtant coverage
doxyxyline
71
what not to take wiht?
kaplan said al too
72
tetracycline mech and penetration
188
73
tetracycline safe in renal failure?
188
74
tetracycline use
188
75
tetracycline adverse effects
188
76
tetracycline resistance
188
77
tetracycline resistance
188
78
tigecycline use
188
79
tigecycline effects
188
80
chloramphenicol mech
188
81
chloramphenicol use
188
82
chloramphenicol effects
188
83
chloramphenicol resistance
188
84
clindamycin improtant coverage mrsa
188
85
clindamcin mechanism
188
86
clindamcin use
188
87
clindamcin effects
188
88
oxazolidinones 2nd line for what?
mrsa, 1st line vancomycin
89
oxazolidinones mech
189
90
oxazolidinones use
189
91
oxazolidinones effects
189
92
oxazolidinones resistance
189
93
macrolide names
189
94
macrolide that doesnt inhibit cyp
189
95
macrolide mech
189
96
macrolide use
189
97
macrolide effects
189
98
macrolide resistance
189
99
urethritis treat with
ceftriaxone + doxycyline or macrolide
100
tmp-smx important coverage
190
101
sulfonamides names
190
102
sulfonamides mech
190
103
sulfonamides use
190
104
dapsone mech
190
105
sulfonamides effects
190
106
sulfonamides resistance
190
107
dapsone use
190
108
dapsone effects
190
109
trimethoprim
190
110
pyremethamine mech
190
111
trimpethoprim use
190
112
trimpethoprim useeffects
190
113
tmp smx in pregancy
190
114
alternative to UTi with tmo smx
nitrofurantoin
115
moxifloxacin works agiasnt?
anerobes
116
fluroquinolone without -floxacin in the name
enoxacin
117
fluroquinolone mech
191
118
fluroquinolone dont take with?
191
119
fluroquinolone use
191
120
fluroquinolone effects
191
121
fluroquinolone resistance
191
122
daptopmycin mech
191
123
daptopmycin use
191
124
daptopmycin resistance
191
125
daptopmycin effects
191
126
metronidazole mech
191
127
metrionidazole effects
191
128
MAC prophylaxis
192
129
MAC treatment
192
130
rafamycins names
192
131
rafamycins mech
192
132
rafamycins use
192
133
rafamycins affects
192
134
rafamycins resistance
192
135
isonizaid mech
193
136
isonizaid isonizaid use
193
137
isonizaid pharmacology
193
138
isonizaid affects
193
139
isonizaid resistance
193
140
isonizaid resistance
193
141
pyrazinamide mech
193
142
pyrazinamide side effect
193
143
ehtambutol mech
193
144
ehtambutol effects
193
145
streptomycin TB
193
146
streptomycin use
193
147
streptomycin tinnitus vertigo aaxia neprotocitcity
193
148
high risk endocarditis dental procedure
amoxicillin
149
expsoure to goorrhea
cetriaxone
150
histoyr of reccurent uti?
tmp smx
151
expsoure to meningicoccal infection
ceftriaxone, ciprofloxacin, rifampin
152
treatment of pregger with group b strep
intrapartum penicillin g or ampicillin
153
prevention of gonoccal conjuctivitis in newborn
erythromycin
154
postsurgical infection due to staph aureus
cafazolin
155
propylaxis of strep pharygitis in child with prior rheumatic fever
benazathine penicillin g or or oral penicillin v
156
syphilliz exposure
benzathing penicillin g
157
ampthoterricin B mech
195
158
ampthoterricin B use
195
159
ampthoterricin B why do you get the side effects
195
160
nystatin mech
195
161
nystatin use
195
162
flucytosine mech
195
163
flucytosine use
195
164
flucytosine side effct
195
165
flucytosine side effct
195
166
fluconazole used for?
195
167
itraconazole for
195
168
topical fungal infections
195
169
voriconazole used for?
195
170
isavuconazole used for?
195
171
azoles effects
195
172
terbinafine mech
blocks conersion of squalene to squalene epoxide by blocking squalene epoxidase
173
terbinafine use
195
174
terbinafine side effects
195
175
echindodins suffix
196
176
echindodins mech
196
177
echindodins use
196
178
echindodins effects
196
179
echindodins effects
196
180
griseofulvin mech
196
181
griseofulvin use
196
182
griseofulvin effects
196
183
suffix for flu drugs
--amivir
184
flu grus mech
197
185
flu grus use
197
186
-virs mech
197
187
-virs use
197
188
-virs for herpes zoster (shingles)
197
189
virs side effects
197
190
virs resistance
197
191
virs u world side effects
197
192
gangciclovir mech
198
193
gangciclovir use
198
194
gangciclovir side effcts
198
195
gangciclovir resistance
198
196
foscarnet mech
198
197
foscarnet use
198
198
foscarnet effects
198
199
foscarnet resistance
198
200
cidofovir mech
198
201
cidofovir use
198
202
cidofovir effects
198
203
indication for hiv therapy
199
204
preferred treatment for HIV
199
205
nrti suffix
-vudine
206
nrti mech
199
207
zidovudine special use
199
208
nrtis
effects
209
nnrtis names
199
210
nnrtis mech
199
211
nnertis effects
199
212
protease inhibitor suffix
199
213
protease inhibitor mech
199
214
protease inhibitor booster
199
215
protease inhibitor pharmaclogicy
199
216
protease inhibitor effects
199
217
integrase inhibitor common nae
-tegr-
218
integrase inhibitor mech and side effects
mec
219
fusion inhbitor name
199
220
fusion inhbitor mech
199
221
fusion inhbitor effects
199
222
docking inhibitor name and mech
199
223
interferons mech
200
224
ifn a use
200
225
ifn b use
200
226
ifn f
200
227
interferons efftcs
200
228
ribavarin mech
200
229
ribavarin use
200
230
ribavarin effects
200
231
sofosbuvir mech
200
232
sofosbuvir use
200
233
sofosbuvir effects
200
234
simeprevir mech
200
235
simeprevir use
200
236
simeprevir effects
200
237
antimicrobials to avoid in pregancy
201
238
cd4 less than 200 prophylaxis
use tmp smx for pneumocystis
239
cd4 less than 100 prohylaxis
tmp and smx for pneumocystis and toxoplasmosis
240
cd4 less than 50 prophylaxis
use azithromycin or clarithromycin for MAC
241
mrsa treatment
vancomycin, daptomycin, linezolid, tigecycline, cefaroline, doxycycline
242
vre treatment
linezolid, streptogamins (quinupristin, dalfopristin) - bind to 50s, i added (daptomycin, linezolid, tigecycline
243
multidrug resistant p aeruginosa
polymixins B and E(colistin)
244
multidrug resistant acinetobacter baumannii
polymixins B and E(colistin)
245
azole for histoplasma, coccidioides, blastomyces
itraconazole
246
topical azole for fungal infections of skin
coltrimazole and miconazole
247
asperigillus infection
voriconazole (also works agaisnt some candida)
serious aspergillus use isavuconazole
248
mucorales infection
amphoterricin
isavuconazole
249
toxoplasmosis treatment
pyrimethamine + sulfadiazine
250
t cruzi
benznidazole or nifurtimox; crusing in my benz with a fur coat on
251
leshminiasis
amphotericin b (localized cutaneous) or sodium stibogluconate (sever diffuse cutaneous and visceral)
252
antimite/louse therapy
permethrin (neuronal membrane deplorization via na channels)
malathion (acetylcholinesterase inhibitor)
lindane (blocks gaba channels -> neurotoxicity)
used to treat scabies (sarco scabiei) and live (pediculus and pthirus)
treat Pesky Mites and Lice with PML because they NAG you
scabies: permethin cream, washing/drying all clothing/bedding, treat close contacts
lice: pyrethoids, malathion, or ivermectin lotion, and nit combing. children can attend school and treated at home
253
malaria treatments
use choloroquine for sensitive species (dont use for falciparum, resistance too common)
if resistant use:
mefloquine, atovaquone/proguanil
Treat falciparum with:
artemether/lumefantrine or atovaquone/proguanil
for life threatening use:
use IV quinidine in US (quinine elsewhere) or artesunate
for p vivax/ovale
add primaquine for hypnozoite
254
chloroquine (hydrozychloroquine)
blocks plasmodium heme polymerase which turns heme into hemozoin. heme accumulates and is toxic.
resistance due to membrane pump that reduces intracellular concentrations
retinopathy; pruitis (especially in dark skinned people)
255
empiric meningitis treatment
ceftriaxone and vancomycin (add ampicillin if listeria suspected)
256
emtricitabine (ftc)
nrti macular rash on palms
257
c tetani treatment
prevent with vaccine. treat with antitoxin plus minus vaccine booster., diazepem (for muscle spasms), wound debridement.
258
c diff treatment
often caused by clindamycin, ampicillin, associated with ppi use.
metronidazole or oral vancomycine. reccurent cases consider fidaxomicin, or fecal microbiota transplant.
259
listeria monocytogenes treatment
ampicillin
260
gonocci treatment
cetriaxone + (azithromycin or doxycyline) for chlamydia
erythromycin oitment prevents neonatal blindness
261
menigocci treatment
rifampin, ciprofloxacin, ceftriaxone for prophylaxis of close contacts.
treat with ceftriaxone or penicillin g
262
haemophilus influenza treatment
amoxicillin +/- claculanate for mucosal infections. ceftriaxone for meningitis. rifampin prophylaxis for close ocntacts.
263
legionella treatment
macrolide or quinolone
264
pseudomonas treatment treatment
"campfire"
carbapenems
aminoglycosides
monobactams
polymyxins (polymixn b, colistin)
fluroquinolones (ciprofloxacin, levofluroquinolone)
thIRd and fourth gen cepahlospoins (eg ceftazidime, cefepime)
extended spectrum peniciilins (eg ticarcillin, piperacillin)
265
salmonella typhi
ceftriaxone or fluroquinolones
266
h pylori
amoxicillin (metronidazole if allergic) + clarythromycin + ppi (antibiotics cure pylori)
267
lyme disease
doxycyline (1st line); amoxicillin and cefuroxime in pregnant women and children
utd says all work for early stage
268
g vaginalis
metro or clindamycin
269
chlamydiae
treatment: azithromycin (prefered because one time treatment) or doxycyline (+ceftriaxone)
lacks classic peptidoglycan due to reducde muramic acid so b lactams dont work
270
m pneumonia
macrolides, doxycyline, or fluroquinionlens.
penicillin infeective since no cell wall
271
candida
oral fluconazole/topical azole for vaginal.
nystatin, fluconazole, or capsofungin for oral/esophageal.
fluconazole, caspofungin, or amphoterricin b for systemic
272
c neoformans
amphoterricin b + flucytosine followed by fluconzaole for meningitis
273
mucor and rhizopus
surgical debridement and amphoterricin b
274
PCP
tmp-smx, pentamidine (if sulfa allergy), dapsone (prophylaxis only), atovaquone. Start prophylaxis when cd4 less than 200
275
sporothrix
itraconazole or k iodide
276
giardia
metro
277
e histolytica
metronidazole; paromomycin or iodoquinol for asymptomatic stool passers
278
cryptosporidium
prevention by filtering city water supplies; nitazoxanide in immunocmopetent hosts
279
toxoplasmosis
tmp smx prophylaxis
sulfadiazine + pyrimethamine
280
n fowleri
amphoterrin b has been effective in a few
281
t brucei
suramin for blood
melarsoprol for CNS
282
babesia
atovaquone + azithromycin
283
t cruzi
benznidazole or nifurtomox
curising in my benz with my fur coat
284
l donovani
amphoterricn b (localized cutaneous)
sodium stibogluconate (severe diffuse cutaneous or visceral)
285
t vaginalis
metronidazole for patient and partner (prophylaxis)
286
enterobius vermiculuari (pin worm)
bendazoles (1st line)
pyrantel pamoate (pregnant)
287
ascaris (giant roundworm)
bendazoles
288
strongyloides (threadworm)
ivermectin or bendazoles
289
ancyclostome/necator (hookworms)
bendazoles or pyrantel pamoate
290
t spiralis
bendazoles
291
trichuris trichiura (whipworm)
bendazoles
292
toxocara canis
bendazoles
293
onchocerca volvulus
ivermectin
294
loa loa
diethylcarbamazine
295
wuchereria bancrofti
diethylcarbamazine
296
t solium
intestinal tapeworm - paziquantel
cystercercosis - praziquantel
neurocystercerci - albendazole
297
d latum
praziquantel
298
e granulosis
albendazole
299
schistoma
praziquantel
300
clonorchis
praziquantel
301
rsv prophylaxis in premies
palivizumab
302
postexposure prohylazin rabies
wound cleaning plus immunization with killed vaccine and rabies immunoglobin
