Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

GIR Test 2 > B5-019 Non-Neoplastic GI Pathology > Flashcards

B5-019 Non-Neoplastic GI Pathology Flashcards

(66 cards)

Start Studying
1
Q

most common pathogens of infectious esophagitis

2

A

HSV-1
candida albicans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

[…] is the hallmark symptom of infectious esophagitis

A

odnynophagia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q
  • micro: viral inclusions in squamous cells at margin of ulcers
  • multinucleation, margination, molding
  • cowdry type A
A

HSV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

gross: shallow vesicles and ulcers

A

HSV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q
  • virus present in endothelium, enlarged stomal cells, and epipthelial cells at ulcer base
  • nuclear and cellular enlargement
  • owl’s eye inclusions
A

CMV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q
A

CMV esophagitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

gray-white plaques/pseudomembranes or ulcers on EGD

A

candida esophagitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

fungal pseudohyphae within the squamous epithelium, neutrophilic inflammation

A

candida esophagitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
A

normal esophagus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q
  • elongation of vascular papillae
  • basal cell hyperplasia
  • eosinophils and neutrophils
A

GERD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

food impaction/dysphagia symptoms in addition to GERD symptoms

A

eosinophilic esophagitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

endoscopy:
* linear furrows
* esophageal rings
* possible strictures

A

eosinophilic esophagitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

erythema, erosions, maybe strictures on EGD

A

GERD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

similar to reflux, but more eosinophils (15ish) in both distal and proximal esophagus

A

eosinophilic esophagitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
  • probable longstanding complication of GERD
  • replacement of normal distal esophageal squamous mucosa with intestinal type glandular mucosa
A

Barrett’s Esophagus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

irregular band of dark pink, velvety mucosa extending upward as tongues of mucosa

A

Barrett’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

metaplastic columnar epithelium with goblet cells

A

Barrett’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q
A

normal gastric body/fundus with parietal and chief cells

pink= parietal, purple=chief

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q
A

normal gastric antrum with G cells and mucus glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

curved, helical gram negative bacilli producing urease

A

H. pylori

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

often appears normal on EGD
may have erythema, nodularity, ulcers

A

H. pylori

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q
  • dense lamina with lymphoplasmacytic infiltrate
  • neutrophils
  • organisms in mucus layer
A

H. pylori

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what part of the stomach are you more likely to find H. pylori in?

A

antrum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

triple therapy for H. pylori

A

2 antibiotics and PPI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
intestinal metaplasia from long standing H. pylori
26
AMAG leads to pernicious anemia due to
decreased B12 absoprtion
27
* affects parietal cells only * causes and increased risk of cancer from NET
AMAG
28
lack of parietal cells, have been replaced by intestinal metaplasia
AMAG
29
* antrum * neutrophils * normal acid/gastrin secretion * hyperplastic/inflammatory polyps * peptic ulcer, adenocarcinoma, MALT | H. pylori or autoimmune
H. pylori
30
* body * lymphocytes/macrophages * decreased acid production * increased gastrin production * NET * pernicious anemia | H. pylori or autoimmune
autoimmune
31
lymphocytes attack small bowel epithelium
celiac disease
32
what HLA types are associated with celiac disorder?
HLA-DQ2 HLA-DQ8
33
cracked earth appearance
celiac
34
* weight loss, edema, muscle wasting * light colored, foul smelling diarrhea
celiac
35
normal small bowel
36
blunting of villi, increased intraepithelial lymphocytes marked crypt hyperplasia
celiac
37
diagnosis of celiac disease
biopsy + anti-TTG and/or anti-gliaden antibodies
38
normal colon
39
chronic condition resulting from complex interactions between intestinal microbiota and host immunity in genetically predisposed individuals that leads to inappropriate mucosal immune activation
IBD
40
* IBD that is confined to the colon * distribution is confluent and starts at left side/rectum
ulcerative colitis
41
* IBD that can involve the entire GI tract * skip lesions, granulomas, deep ulcers with strictures
Crohn's Disease
42
* crypt architectural distortion * basal lamina propria lymphoplasmacytosis * neutrophils in active disease
chronic colitis | Chron's or UC
43
treatment for chronic colitis
anti-inflammatory and immunosuppressants; TNF-a
44
causes furrowing of the esophagus
eosinophilic esophagitis
45
official number of eosinophils needed for diagnosis of eosinophilic esophagitis
15 per high power field
46
cause white plaques in esophagus in immunocompromised patients
candida
47
involves the whole tubal gut
Chron's
48
limited to colonic involvement
ulcerative colitis
49
ulceration and acute inflammation of the terminal ileum is more likely to be associated with | chrons or UC
Crohns
50
diffuse inflammation of the distal colon (sigmoid-rectum) only
ulcerative colitis
51
multinucleate squamous cells with chromatin margination
HSV esophagitis
52
* well circumscribed ulcers in the distal esophagus with flat borders * odynophagia * immunocompromised patient | 2
CMV or HSV
53
atypical glands infiltrating the submucosa
adenocarcinoma
54
mass like ulceration and dysphagia
adenocarcinoma
55
fungal elements on PAS/D stain
candida
56
more than 15 eosinophils per high powered field
eosinophilic esophagitis
57
* cracked earth appearance of duodenum * blunted duodenal villi with increased intraepithelial lymphocytes
celiac
58
trial of six food elimination diet is a therapeutic option for
eosinophilic esophagitis
59
* attentuated crypt epithelium * hyalinized lamina propria
acute ischemic colitis
60
basal lymphoplasmacytosis
IBD colitis
61
increased intraepithelial lymphocytes
lymphocytic colitis | causes chronic watery diarrhea
62
* mucosal granulomas * submucosal lymphoid aggregates
Crohn's
63
treatment for lymphocytic colitis
immunosuppression with corticosteroids
64
* chronic gastritis * urea breath test is positive
H. pylori
65
treatment for H. pylori
triple therapy with omeprazole and two antibiotics
66
* macrocytic anemia * elevated gastrin * positive anti-parietal antibody
AMAG

GIR Test 2 (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions