Bacterial Causes of Cystitis Flashcards

(42 cards)

1
Q

What is the definition of cystitis?

A

Inflammation of the bladder

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2
Q

What does cystitis mainly affects

A
  • affects animals and people of both sexes and ages
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3
Q

What are the main causes of cystitis

A
  • Bacteria
  • Fungi/Yeast
  • Parasites
  • Trauma
  • Toxins
  • Neoplasia
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4
Q

What percentage of a herd is likely to be affected by cystitis

A

1-2% of the cows

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5
Q

What predisposes to cystitis?

A
  • Bladder stones
  • Chronic UTI
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6
Q

What species are most susceptible to cystitis?

A

Dogs, Cats, Guinea-Pigs

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7
Q

What has an effect on whether a species is predisposed to cystitis?

A

Positioning of the urethra

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8
Q

What are some of the clinical signs of cystitis?

A
  • Polkaiuria
  • haematuria
  • stranguria
  • dysuria
  • urinating in public places
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9
Q

Why does cystitis not occur all the time?

A
  • Dependent on the bugs being in the wrong place at the wrong time
  • usually the body can remove the bugs
  • cystitis requires multiple predisposing factors- e.g immunosupression with virulence
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10
Q

What may an owner notice in an animal with cystitis

A

Urinating all the time

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11
Q

What clinical signs are seen if cystitis has a bacterial component?

A
  • abnormal urine
  • pyrexia
  • cloudy urine
  • lethargy/ anorexia
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12
Q

Where is haematuria noticed?

A

end of the urine stream

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13
Q

What may a bladder with cystitis feel like?

A

thickened or irregular

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14
Q

What is acute cystitis?

A

catarrhal inflammation
may be haemorrhagic
some mild cases resolve others lead to chronic cystitis

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15
Q

What two types of chronic cystitis are there?

A
  • Polypoid
  • Follicular
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16
Q

What is emphysematous cystitis?

A

related to animals with diabetes mellitus
-fermentation of sugar by glucose-fermenting bacteria

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17
Q

What is feline idiopathic cystitis?

A

Neurological changes in the spinal pain fibres as well as the bladder wall

18
Q

What is a recurrent infection

A

A recurrent infection caused by the same bacterial organism is termed
a relapse and is essentially a treatment failure.

19
Q

What typically causes a relapse?

A
  • inappropriate antibiotic therapy
  • or an unrecognised complicating factor
20
Q

What is the most common bacterial cause of cystitis

21
Q

What does proteus look like?

A
  • Gram neg
  • faculative anaerobe
  • rod-shaped
  • has important appendages- common in animals with cystitis- they stick to the mucosa of bladder tissue
22
Q

What is the pathology of porcine cystitis

A

Cystitis, chronic-active, diffuse, mild, with epithelial
hypertrophy, mucinous metaplasia and micro-abscesses,
breed not specified, porcine.

23
Q

Where does eubacterium usually inhabit?

A

prepuce tissue

rarely causes disease in males

24
Q

What is enterobacter?

A

gram negative, faculatuvely anerobic

25
What is enterococci
Gram positive, cocci shaped, faculatively anerobic
26
What is the most important E.Coli pathotype?
UPEC
27
What is polyploid cystitis?
* a type of chronic cystitis seen in most species * gross pathology shows polyp like projections from the mucosa
28
What is follicular cystitis?
is a chronic cystitis of unknown aetiology common in the dog.
29
What is the main issue that the damage that UPEC does to the tissue wall?
Shedding of the wall= shedding of organisms = reinfection in other animals
30
What is staphylococcus?
Gram positive, aerobic, cocci shaped bacterium can cause sloughing of tissue and therefore blockages
31
What is streptococcus?
Gram positive, faculative anerobic, cocci shaped bacterium
32
What is klebsiella?
Gram engative, faculative anaerobic, rod shaped bacterium all animals pecies are susceptible it makes the urine smell sweet
33
What is Corynebacterium renale?
* faculative anaerobic, rod shaped filamentous bacterium * Cattle * lives in the prepuce and semen of asymptomatic bulls
34
What is the most common risk factor for cystitis?
Normally because of fetal contamination after parturition
35
What is the preffered method for sample collection?
cystocentesis followed by sterile urethral catheterisation or a midstream free catch
36
What is the second most common bacteria in UTI's?
Pseudomonas * Gram negative * aerobic * rod-shaped * many animal species are susceptible
37
What do haemophillus look like?
* Gram negative, faculative anaerobe, rod-shaped bacterium
38
What animal is eubacterium suis a pathogen of?
Pathogen of pigs only * it can be isolated from the diverticulum in male pigs over 10 weeks
39
What adaptation does UPEC contain?
contains polynephritis fimbriae and can therefore replicate in bladder cells
40
What bacteria contains fimbriae allowing them to stick to the inside of the bladder (and replicate)
UPEC
41
What is the consequence of UPEC being intracellular?
harder to treat, antibiotics may not be able to get inside of the cell
42
When may the urine pH be alkaline?
If the bacteria is urease positive