Barrett's Oesophagus Flashcards Preview

Gastrointestinal > Barrett's Oesophagus > Flashcards

Flashcards in Barrett's Oesophagus Deck (7)
Loading flashcards...
1

What is Barrett's oesophagus.

A premalignant change from squamous cells to columnar cells in the lower oesophagus. (metaplasia).
It forms a segment of 'columnar-lined oesophagus' (CLO).
The length affected may be a few centimetres, to the entire oesophagus.

2

What is Barrett's oesophagus due to. (2)

It is secondary to chronic GORD - due to prolonged exposure to the refluxate of GORD. (a complication of GORD) - it is found in 10% of patients undergoing gastroscopy for reflux symptoms.
Central obesity is a risk factor.

3

What is a complication of Barrett's oesophagus.

Adenocarcinoma. However, this seems to relate to the severity and duration of the reflux, rather than the condition of Barrett's oesophagus per se.
The risk of progression is low: 0.6-1.6% per year in patients with low grade dysplasia.

4

What is the prevalence of Barrett's oesophagus.

1.5-5% of the population.

5

Who is Barrett's oesophagus usually found in. (4)

It is more common in men (especially white).
Over 50.
Obese individuals.
It is weakly associated with smoking, but has no relation to alcohol intake.
It is found in 10% of patients undergoing gastroscopy for reflux symptoms.

6

What is another common finding alongside Barrett's oesophagus.

A hiatus hernia is almost always present.

7

What percentage of GORD patients go on to develop Barrett's oesophagus.

3-5%