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Rabbits > BB LRGPHOR Ch14 - Rabbit Viral Diseases > Flashcards

BB LRGPHOR Ch14 - Rabbit Viral Diseases Flashcards

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1
Q
  1. Myxoma virus in rabbits results in a severe, systemic disease in which species: a. Lepus tinidus b. Sylvilagus braziliensis c. Oryctolagus cuniculus d. Sylvilagus floridanus
A

c

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2
Q
  1. Which of the following contains only intracytoplasmic inclusions? a. Myxoma virus b. Rabbit Hemorrhagic Disease Virus c. Rabbit Oral Papillomavirus d. Herpesvirus cuniculi e. Rabbit Kidney Vacuolating Virus
A

a. Myxoma virus

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3
Q
  1. Which virus closely resembles Shope fibromatosis in Sylvilagus species, but causes a rapid, fatal infection in Oryctalagus species?
A

Myxoma virus

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4
Q
  1. What is a diagnostic distinction between Shope fibromatosis and papillomatosis in rabbits?
A

Presence of intranuclear inclusions

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5
Q
  1. Which of the following viruses of rabbits in the family Poxviridae is an Orthopoxvirus? a. Hare Fibroma Virus b. Rabbit (Shope) Fibroma Virus c. Myxoma Virus d. Rabbit Poxvirus
A

d. Rabbit Poxvirus

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6
Q
  1. Indicate whether the following viruses are DNA or RNA viruses: a. Rabbit Hemorrhagic Disease Virus b. Rabbit Fibroma Virus c. Leporid Herpesvirus 1 d. Rotavirus e. Lapine parvovirus f. Shope Papillomavirus
A

a. Rabbit Hemorrhagic Disease Virus - RNA b. Rabbit Fibroma Virus - DNA c. Leporid Herpesvirus 1 - DNA d. Rotavirus - RNA e. Lapine parvovirus - DNA f. Shope Papillomavirus - DNA

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7
Q
  1. Which of the following viruses is anthropozoonotic in humans and rabbits? a. Poxvirus b. Herpesvirus c. Papillomavirus d. Calicivirus
A

b

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8
Q
  1. To what genus does Cottontail Rabbit Papillomavirus belong? a. Papillomavirus b. Polyomavirus c. Kappapapillomavirus d. Betapapillomavirus
A

c

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9
Q
  1. True or False: Rabbit Oral Papillomavirus is immunologically identical to Cottontail Rabbit Papilomovirus.
A

FALSE

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10
Q
  1. Which of the following in nonpathogenic for all rabbit species? a. Rabbit Kidney Vacuolating Virus b. European Brown Hare Syndrome Virus c. Leporid parvovirus 4 d. Rabbit Hemorrhagic Disease Virus
A

a

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11
Q
  1. Which of the following is not typically a cause of diarrhea in young rabbits? a. Rabbit Hemorrhagic Disease Virus b. Rotavirus c. Coronaviral enteritis d. Colibacillosis
A

a

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12
Q
  1. Which of the following is most effective at eliminating rotavirus? a. Chlorine b. Formalin c. 95% Ethanol d. Betapropriolactone
A

c

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13
Q
  1. Which of the following is not a pathologic lesion associated with rotavirus? a. Intestines markedly congested and distended b. Villous blunting c. Mucosal hemorrhages d. Proliferative ileitis
A

d

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14
Q
  1. True or False: It is possible to rederive rabbits free of rotaviral infection through early weaning.
A

True

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15
Q
  1. Which of the following types of viruses may be a useful model for virus-induced cardiomyopathy? a. Coronavirus b. Calicivirus c. Parvovirus d. Bunyavirus
A

a

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16
Q
  1. The “etiologic agents of necrotic hepatitis of leporids” are classified as what type of viruses? a. Calicivirus b. Coronavirus c. Flavivirus d. Herpesvirus
A

a

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17
Q
  1. What is the most consistent finding in Rabbit Hemorrhagic Disease Virus?
A

Pale liver with periportal necrosis

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18
Q
  1. Which of the following viruses does not result in clinical disease in rabbits? a. European Brown Hare Syndrome Virus b. Rabbit Calicivirus c. Michigan Rabbit Calicivirus d. Rabbit Hemorrhagic Disease Virus
A

Rabbit Calicivirus

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19
Q
  1. Which of the following rat viruses do rabbits develop antibodies to? a. Sendai virus b. Rat Respiratory virus c. Sialodacryoadenitis Virus d. PVM
A

a

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20
Q
  1. Which of the following species is not involved in perpetuation of the flavivirus, Powassan virus? a. Peromyscus leucopus b. Lepus americanus c. Marmota monax d. Octodon degus
A

d

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21
Q

Causative agent of myxomatosis

A

Myxoma virus

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22
Q

Characteristics of myxoma virus

A

Family Poxviridae, genus Leporipoxvirus Enveloped double stranded DNA virus

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23
Q

Clinical signs of myxomatosis

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A

Oryctolagus - mucinous skin lesions and tumors, edema around mouth, nose, anus, genitals progressive conjunctivitis

24
Q

Epizootiology of myxoma virus

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A

Oryctolagus particularly susceptible flea and mosquito vectors, direct contact Sylvilagus and Lepus spp. naturally susceptible

25
Pathogenesis of myxomatosis
immunomodulatory proteins inhibit apoptosis, leukocyte chemotaxis, leukocyte activation
26
Pathology of myxomatosis
myxomas - undifferentiated stellate mesenchymal cells embedded in mucinous matrix with capillaries and inflammatory cells
27
Diagnosis of myxomatosis
PCR, ELISA, culture virus from tissue
28
Differential diagnosis of myxomatosis
In Sylvilagus, lesions indistinguishable from rabbit fibroma virus - fibroma. Inoculate Oryctolagus with material to determine if it is myxoma virus (fatal) or fibroma virus (fibroma)
29
Characteristics of Shope fibroma virus
Family Poxviridae, genus Leporipoxvirus similar to myxoma virus Enveloped, double stranded DNA virus
30
Epizootiology of Shope fibroma virus
endemic in wild rabbits - causes fibromas skin tumors in domestic rabbits arthropod vectors spontaneously regress
31
Clinical signs of Shope fibroma virus
flat, subcutaneous, easily movable tumors on legs and face
32
Characteristics of rabbit pox virus
Family Poxviridae, genus Orthopoxvirus
33
Clinical signs of rabbit pox virus
fever nasal discharge eye lesions - blepharitis, conjunctivitis, keratitis widespread skin lesions - macules/papules rash enlarged lymph nodes, facial edema
34
Pathology of rabbit pox virus
nodules on liver, gall bladder, spleen, lung, repro organs widespread necrosis Cytoplasmic inclusions are reare
35
Characteristics of Shope papilloma virus
Family Papovaviridae, genus Kappapapilomavirus nonenveloped double stranded DNA virus
36
Clinical signs of Shope papilloma virus
horny warts an the neck, shoulders abdomen
37
Epizootiology of Shope papilloma virus
widespread geographic distribution SCC in Sylvilagus spp. arthropod vector
38
Characteristics of rabbit rotavirus
Family Reoviridae, group A, serotype 3 Nonenveloped double stranded RNA virus
39
Clinical signs of rabbit rotavirus
anorexia, dehydration, watery to mucoid diarrhea, death
40
Epizootiology of rabbit rotavirus
weanlings most susceptible newborns resistant due to passive immunity
41
Pathology of rabbit rotavirus
villous atrophy, loss of small intestinal epithelial cells' lymphocytic infiltrate
42
Diagnosis of rabbit rotavirus
immunoassays
43
Characteristics of rabbit coronavirus
Family Coronaviridae Enveloped single stranded RNA virus
44
Causative agent of rabbit hemorrhagic disease
Rabbit hemorrhagic disease virus family Caliciviridae nonenveloped single stranded RNA
45
Clinical syndromes of rabbit hemorrhagic disease
1. acute - anorexia, depression, neuro and resp. signs, ocular hemorrhage, epistaxis 2.peracute - sudden death 3. subacute - mild clinical signs
46
Epizootiology
first described in China 1984 now widespread in Europe, Asia, Africa, Australia, NZ fecal oral transmission suspected fomite and arthropod vectors
47
Pathology of rabbit hemorrhagic disease virus
periportal hepatic necrosis DIC, thrombosis
48
Diagnosis of rabbit hemorrhagic disease
electron microscopy of liver tissue ELiSA
49
Differential diagnosis of rabbit hemorrhagic disease
European brown hare virus (calicivirus)
50
This clinical condition is caused by what kind of virus? a. polyomavirus b. calicivirus c. rotavirus d. papillomavirus
b. calicivirus Rabbit hemorrhagic fever genus: Lagovirus
51
Taxonomy of causative agent of this histopathology
Family Poxviridae Genus Leporipoxvirus
52
which genus of rabbit is most susceptible to this diseasse? a. Lepis b. Sylvilagus c. Oryctolagus d. Bunolagus
c. Oryctolagus
53
What is the genus of agent that causes this clinical presentation: a. Leporipoxvirus b. Orthopoxvirus c. Kappapapillomavirus-1 d. Kappapapillomavirus-2
c. Kappapapillomavirus-1
54
What is the mode of transmission of the agent that causes this histopathologic presentation? a. horizontal (placental) b. fecal-oral c. exposure to spores in the environment d. arthropod vector
b. fecal-oral Rabbit hemorrhagic fever virus
55
Arrows pointing to intranuclear inclusion bodies associated with what agent? a. Leporipoxvirus b. Kappapapillomavirus-1 c. Orthopoxvirus d. Kappapapillomavirus-2
a. Leporipoxvirus (Shope Fibroma virus)
56
Causative agent of this condition: a. Leporipoxvirus b. Orthopoxvirus c. ppapapillomavirus d. Psoroptes
a. Leporipoxvirus

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