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PB Ch6 Rabbit Flashcards

1
Q

How can members of the order Lagomorpha be differentiated from the order Rodentia?

A

An additional pair of incisor teeth is located directly behind the large incisors on the upper jaw.

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2
Q
  1. Give the genus and species name of the domestic rabbit.
A

Oryctolagus cuniculus

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3
Q
  1. Which of the following most accurately describes aspects of the rabbit which make it a good research model?
    a. Large ears
    b. Readily accessible blood vessels
    c. Ideal candidate for antibody production and blood collection
    d. Blood flow to the ears is the primary means of temperature control
    e. All of the above
A

e

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4
Q
  1. The majority of rabbits used for research are of the ___________ breed.
A

New Zealand White

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5
Q
  1. Give the term of the practice used by domestic rabbits in recycling protein and B complex vitamins.
A

cecotrophy

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6
Q
  1. The mean lifespan of rabbit erythrocytes is _______ days.
A

50

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7
Q
  1. The rabbit counterpart for the neutrophil is a __________________.
A

heterophil

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8
Q
  1. Basophils may represent up to _______% of circulating leukocytes.
A

30%

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9
Q
  1. __________________ are usually the predominant leukocyte in the peripheral blood of domestic rabbits.
A

lymphocytes

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10
Q
  1. Rabbits are a (fore, mid or hind) gut fermenter.
A

hind

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11
Q
  1. Name the spherical, thick-walled enlargement which is found at the ileocecal junction of rabbits.
A

sacculus rotundus

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12
Q
  1. The ______________ ____________ is a round patch of lymphoid tissue adjacent to the cecum.
A

cecal tonsil

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13
Q
  1. The _____________ is found at the tip of the cecum.
A

appendix

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14
Q
  1. GALT stands for _______-__________________ _________________ _______________
A

gut-associated lymphoid tissue

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15
Q
  1. Brunner’s glands are found in what portion of the small intestine?
A

duodenum

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16
Q
  1. The pH of rabbit urine is (acidic, alkaline) and contains ____________________ and ___________________ (what type) crystals.
A

alkaline;

primarily calcium carbonate monohydrate and ammonium magnesium phosphate (triple phosphate) crystals after rabbits begin eating solid food

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17
Q
  1. Dark reddish, orange urine is found in the rabbit’s pan liner? What do you suspect is the cause?
    a. Normal urine only
    b. Elevated levels of urobilin
    c. Hematuria
    d. Could be associated with any of the above
A

d

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18
Q
  1. The rabbit placentation is
    a. endotheliochorial
    b. hemochorial
    c. hemoendothelial
    d. epitheliochorial
A

Rabbit placentation is hemoendothelial.

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19
Q
  1. The _______________________ virus is a benign disease of cottontail rabbits and is used as a model for papillomatosis and virus-induced malignancy. It produces papillomas with a high incidence of progression to squamous cell carcinoma.
    a. Adenomavirus
    b. Adenovirus
    c. Polyomavirus
    d. Papillomavirus
A

d. Papillomavirus

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20
Q
  1. The natural host of rabbit (Shope) papillomatosis is:
    a. Oryctolagus
    b. Sylvilagus
A

b. Sylvilagus

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21
Q
  1. The most common oral location for pedunculated oral papillomatosis lesions in domestic rabbits is:
    a. dorsal tongue
    b. maxillary gingiva
    c. mandibular gingiva
    d. ventral tongue
A

d

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22
Q
  1. Which of the following virus types has been isolated from primary rabbit kidney cultures?
    a. Pox virus
    b. Adenovirus
    c. Parvovirus
    d. Polyoma virus
A

d

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23
Q
  1. Give the genus and species name of the “brush rabbit”.
A

Sylvilagus bachmani

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24
Q
  1. What infectious agents of rabbits has been used as a means of biological control for a specific population of rabbits?
A

Myxomatosis virus

Rabbit calicivirus - Rabbit Hemorrhagic Disease

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25
25. Vectors for transmission of myxomatosis include _____________ and \_\_\_\_\_\_\_\_\_\_\_\_\_\_.
fleas and mosquitos
26
26. Shope fibroma virus was first isolated from a cottontail rabbit (provide genus and species name) in the US in 1932..
Sylvilagus floridanus
27
27. The primary site for viral replication of rabbit pox in the naturally occurring disease is the \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_.
respiratory tract
28
28. True or False???? Herpes sylvilagus replicates well in kidney cells prepared from the domestic rabbit, however viral infection of the NZW rabbit has not been successful.
True
29
29. Rabbit hemorrhagic disease (RHD) is caused by a: a. calicivirus b. picornavirus c. herpesvirus d. poxvirus
calicivirus
30
30. Which of the following diseases have been used as a form of biological control for wild rabbit populations? a. Rabbit pox b. Myxomatosis c. Rabbit hemorrhagic disease d. Leporid Herpesvirus 1 infection e. both a and b f. both b and c g. all of the above
f
31
31. Coronavirus infection may be associated with which of the following clinical syndromes: a. enteritis b. pleural effusion c. cardiomyopathy d. all of the above
d
32
32. Rotaviral infection is usually confined to what animal age groups?
sucklings and weanlings
33
33. Snuffles, atrophic rhinitis, suppurative otitis media, and genital tract infection are characteristic clinical signs of infection with \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_.
Pasteurella multocida
34
34. True or False: Localized suppurative bronchopneumonia is naturally produced in rabbits inoculated intranasally with Bordetella bronchiseptica.
False - experimentally-induce in cortisone treated rabbits
35
35. CAR Bacillus infection can be demonstrated best by which of the following techniques? a. silver stain b. H & E stains c. electron microscopy d. both a & b e. both a & c
e
36
36. List 4 of the eight agents now recognized to play a role in the “enteritis complex” of rabbits.
rotaviruses, coronaviruses, Clostridium, E. coli, Lawsonia, Salmonella, Vibrio, coccidian
37
37. The most common clostridial pathogen associated with the enteritis complex in juvenile rabbits is: a. C. difficile b. C. spiroforme c. C. perfringens d. E. coli
b
38
38. Which of the following microscopic staining methods yields a better demonstration of the characteristic bundles of filamentous bacilli associated with Tyzzer’s disease? a. Warthin-Starry silver method b. Giemsa c. H & E d. both a and b e. both b and c
d
39
39. Which of the following characteristics is NOT consistent with enteropathogenic (EPEC) strains of E. coli? a. cause intestinal disease b. produce enterotoxins c. not enteroinvasive d. none of the above
b. produce enterotoxins
40
40. True or False: Dutch Belted rabbits naturally infected with enterohemorrhagic strains of E. coli develop renal disease similar to the hemolytic-uremic syndrome seen in humans.
True
41
41. What methods can be used to identify bacteria in the apical cytoplasm of the crypt-villus column? a. Silver stains b. Periodic-acid Schiff stain c. Electron microscopy d. All of the above
d
42
42. Which of the following diseases is associated with the following clinical signs: succussion splash, teeth grinding, cecal impaction, cecal dysbiosis and accumulation of large quantities of gelatinous mucus in the colon? a. Salmonella b. Vibrio c. Mucoid enteropathy d. Listeriosis
c
43
43. Abortion and sudden death , particularly in does in advanced pregnancy, are characteristic signs of \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_.
Listeriosis
44
44. “Sore hocks”, or ulcerative pododermatitis, is associated with __________________ infections.
staphylococcal
45
45. Rabbit syphyllis or “vent disease” is caused by \_\_\_\_\_\_\_. How is diagnosis confirmed?
Treponema paraluiscuniculi Dark-field examination of wet mounts is recommended Silver staining, Plasma Reagin Antibody Test, & Fluorescent Treponemal Antigen Test are also available
46
46. True or False: Helicobacter does not infect domestic rabbits.
False
47
47. Yersinia pseudotuberculosis is transmitted via: a. ingestion of contaminated food or water b. contaminated bedding c. vector
a
48
48. True or False: Isospora is the most common genus of coccidia seen in rabbits.
False; Eimeria is more common
49
49. What are the two most common pathogenic species of intestinal coccidia in rabbits?
E. intestinalis, E. flavescens
50
50. Enterocyte repair in surviving rabbits following experimental infection with E. intestinalis takes: a. 2 days b. 6 days c. 14 days d. 21 days
c
51
51. Which of the following represents the range of prepatent periods for species of Eimeria in rabbits? a. 5-12 days b. 2-3 weeks c. 1-7 days d. 4-5 weeks
a
52
52. True or False: Clinical signs of Eimeria infection in rabbits is mostly frequently observed in neonatal kits.
False; observed in post-weaning period
53
53. In rabbits, why does dissemination of “night feces” not seem to play a big role in transmission of coccidia?
oocytes sporulate at room temperature
54
54. True or False: In rabbits, immunity against one strain of Eimeria gives protection against other strains.
False
55
Microscopic changes associated with intestinal Eimeria infections in rabbits are typically found where?
Caudal half of small intestine and cecum
56
56. Which of the following can be used to diagnose coccidial infections in rabbits? a. Fecal flotation b. Mucosal scrapings c. Histopathology d. All of the above
d
57
57. What is the most significant genus and species causing hepatic coccidiosis?
Eimeria stiedae
58
58. How soon after ingestion of sporulated oocyts can sporozoitesbe observed in the liver? a. 12 hrs b. 24 hrs c. 48 hrs d. 96 hrs
c
59
59. True or False: In hepatic coccidiosis schizogony occurs in epithelial cells of the bile ducts.
True
60
60. What is the prepatent period of Eimeria stiedae? a. 5-7 days b. 15-18 days c. 2-3 weeks d. 4-6 weeks
b
61
61. True or False: E. stiedae most commonly infects weanling rabbits.
True
62
62. True or False: Raised, linear bosselated, yellow to gray circumscribed lesions scattered throughout the parenchyma of the liver accurately describes hepatic coccidiosis gross liver findings.
True
63
63. True or False: In rabbits infected with E. stiedae, infected bile ducts have hypoplastic epithelium with papillary projections.
False; hyperplastic epithelium
64
64. True or False: Histologic changes induced by E. stiedae are pathognomonic.
True
65
65. True or False: E. cuniculi is an obligate intracellular microsporidian.
True
66
66. What are characteristic features of E. cuniculi that have caused taxonimists to place it as a microsporidian and not a protozoa?
Absence of diplokarya observed in protozoa and presence of coiled polar filament in the mature spore stage
67
67. Encephalitozoonosis causes a more severe disease in which of the following animals? a. Mice and monkeys b. Pigs and monkeys c. Mice and guinea pigs d. Dogs and monkeys
d
68
68. True or False: E. cuniculi can infect rabbits by both oral and respiratory routes.
True
69
Initially, which of the following are the main target organs of E. cuniculi? a. Brain, liver, kidney b. Liver, spleen, lung c. Lung, liver, kidney d. Lung, brain, spleen
c. Lung, liver, kidney Those with high blood flow
70
True or False: E. cuniculi spores survive for less than 1 week at 4C, but may remain viable for at least 6 weeks at 22C
True
71
71. Which of the following best describes the histological lesions observed with E. cuniculi? a. Granulomatous b. Plasmacytic c. Lymphocytic d. Suppurative
a
72
72. True or False: E. cuniculi spores are gram positive.
True
73
73. What colour does carbol fuchsin stain E. cuniculi spores?
Purple
74
74. True or False: CNS involvement of E. cuniculi occurs very quickly after infection.
False; 30 d post-exposure
75
75. In rabbits infected with E. cuniculi, uvetis and cataracts are a common finding in which of the following breeds: a. New Zealand Whites b. Cottontails c. Hares d. Dwarf rabbits
d
76
76. What staining differentiates Toxoplasma from E. cuniculi?
Toxoplasma: Gram negative, PAS negative, stains well with H&E E. cuniculi: Gram positive, PAS positive, does NOT stain well with H&E, are acid fast
77
77. Which of the following is the most widely used diagnostic test for E. cuniculi? a. Serology b. PCR c. Intradermal skin test d. Culture
a
78
78. True or False: There are confirmed cases of E. cuniculi infection in human AIDS patients.
True
79
79. True or False: Cyptosporidia is a common primary pathogen in rabbits.
False
80
80. What is the natural host for Baylisascaris procyonis?
Racoon
81
81. True or False: Embryonation of B. procyonis is a rapid process.
False; takes 30 d
82
82. How long can a B. procyonis egg survive in the environment? a. 3 weeks b. 1 year c. 6 months d. 3 months
b
83
83. True or False: Humans are at risk of zoonosis from rabbits infected with B. procyonis.
False; rabbit is a dead end host
84
84. True or False: Psoroptes cuniculi spends its entire life span in the external ear.
True
85
85. How is P. cuniculi most easily diagnosed?
Wet mount prep from ear
86
86. Which stage of Sarcoptes scabiei evokes a hypersensitivity reaction?
The feeding activity of larvae and nymphs
87
87. Give two contributing factors to barbering.
Boredom and low roughage diets
88
88. True or False: Exfoliative dermatosis is a pruritic skin disease.
False
89
89. Which bacteria is most commonly associated with ulcerative pododermatitis?
Staph. aureus
90
90. Where is the most common site of vertebral fracture/dislocation?
Lumbosacral region (L7)
91
91. What is the common name for Trichobezoar?
Hairball
92
92. List 4 contributing factors to the development of gastric trichobezoars.
Insufficient dietary roughage, excessive grooming, poor gastric motility, sedentary lifestyle
93
93. In which breed of rabbit has cardiomyopathy associated with ketamine/xylazine administration been observed?
Dutch Belted
94
94. Finding pale mineralized streaks in musculature on post-mortem in a rabbit would be consistent with which disease?
Vitamin E deficiency
95
95. List 4 predisposing factors to pregnancy toxemia.
obesity, fasting, hereditary disposition, impaired blood flow to uterus, pituitary dysfunction
96
96. Mild anemia, tremors and posterior ataxia is consistent with which toxicosis?
Lead
97
97. Congenital glaucoma is most common in which breed?
New Zealand White
98
98. True or False: Congenital glaucoma is known to be a painful condition.
False
99
99. Which of the following describes the inheritance of congenital glaucoma: a. Sex linked b. Autosomal recessive with complete penetrance c. Autosomal dominant d. Autosomal recessive, with incomplete penetrance
d
100
100. In rabbits with malocclusion the _________ is abnormally long relative to the \_\_\_\_\_\_\_\_\_\_.
mandible, maxilla
101
101. What is the most common spontaneous tumor occurring in Oryctolagus cuniculus?
Uterine adenocarcinoma
102
102. Uterine adenocarcinomas usually spread to the: a. Lung and liver b. Lung and kidney c. Kidney and liver d. Lung and bone
a
103
103. Which virus is associated with lymphoproliferative disorders in cottontail rabbits?
Herpesvirus sylvilagus
104
104. True or False: Thymomas are a common tumor indomestic rabbits.
False
105
105. Teat and mammary gland enlargement are often associated with which tumor?
pituitary gland tumors

Rabbits (16 decks)

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