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Pharm I > Behavioral Modifiers > Flashcards

Behavioral Modifiers Flashcards

1
Q

Clomipramine MOA

A

tricyclic antidepressant (TCA) - blocks reuptake of serotonin and NE

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2
Q

Clomipramine therapeutic use

A

separation anxiety
compulsive disorders
urine spraying - cats
anxiety
aggression

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3
Q

Clomipramine adverse effects

A

sleepiness
Antimuscarinic effects

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4
Q

Clomipramine drug interactions

A

do not combine with SSRIs

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5
Q

Fluoxetine MOA

A

SSRI

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6
Q

Fluoxetine therapeutic use in dogs

A

separation anxiety
compulsive disorders
acral lick granuloma
aggression

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7
Q

Fluoxetine therapeutic uses in cats

A

urine spraying
inter-cat aggression
compulsive behavior

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8
Q

Fluoxetine adverse effects

A

sleepiness
decreased appetite
serotonin syndrome

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9
Q

Which species is most sensitive to serotonin syndrome

A

felines

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10
Q

Selegiline MOA

A

irreversible MOA-B inhibitor

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11
Q

Selegiline therapeutic use

A

dogs: cognitive dysfunction, fear/phobias

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12
Q

Selegiline adverse effects

A

wakefulness
mildk GIT effects

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13
Q

Dexmedetomidine MOA

A

a2 adrenergic agonist - reduced NE action in locus ceoruleus of brainstem

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14
Q

Dexmedtomidine therapeutic use

A

sileo gel - noise adversion in dogs

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15
Q

Trazodone MOA

A

serotonin 2A antagonist and reuptake inhibitor
alpha 1 adrenergic anatagonist
antihistamine properties

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16
Q

Trazodone therapeutic use

A

adjunct or single agent
anxiety
vet visits (cats)
post-op confinement

17
Q

Trazodone adverse effects

A

sleepiness
serotinin syndrome (drug interaction)

18
Q

Imepitonin MOA

A

GABA agonist

19
Q

Imepitonin therapeutic use

A

noise aversion
anticonvulsant

20
Q

Imepitonin adverse effects

A

sedation
polyphagia

21
Q

Benzodiazepines MOA

A

GABA-A agonists

22
Q

Benzodiazepines therapeutic uses

A

anti-anxiety

23
Q

Buspirone MOA

A

5-HT 1A agonist

24
Q

Buspirone therapeutic use

A

anxiolytic

25
Q

Clonidine MOA

A

a2 agonists

26
Q

Clonidine therapeutic use

A

anxiety
fear/phobias

Pharm I (15 decks)

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